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HMOX2 and GIT1
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
HMOX2
GIT1
Description
heme oxygenase 2
GIT ArfGAP 1
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
Mitochondrion
Cytosol
Focal Adhesion
Membrane
Calyx Of Held
Molecular Function
Heme Oxygenase (decyclizing) Activity
Protein Binding
Heme Binding
Metal Ion Binding
GTPase Activator Activity
Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Response To Hypoxia
Heme Oxidation
Cellular Iron Ion Homeostasis
Response To Oxidative Stress
Heme Catabolic Process
Neutrophil Degranulation
Iron Ion Homeostasis
Intramembranous Ossification
Brain Development
Locomotory Behavior
Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Cytokinesis
Negative Regulation Of Interleukin-1 Beta Production
Positive Regulation Of GTPase Activity
Cell Redox Homeostasis
Negative Regulation Of Glycolytic Process
Ephrin Receptor Signaling Pathway
Neuron Development
Motor Learning
Cellular Response To Lipopolysaccharide
Presynaptic Modulation Of Chemical Synaptic Transmission
Negative Regulation Of Inflammatory Response To Wounding
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Heme degradation
Neutrophil degranulation
Iron uptake and transport
Ephrin signaling
Ephrin signaling
Activation of RAC1 downstream of NMDARs
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
Adult body size (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ELOVL5
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LMNA
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
52 interacting genes:
ARHGEF6
ARHGEF7
BARD1
C8orf33
CCDC113
CDC42
CENPU
CEP126
CHD3
DDX24
EIF6
ENTR1
GIT2
GRB2
GRK2
GRK3
GRK5
GRK6
HAP1
HMOX2
HTT
KIF1A
LAMTOR5
LPXN
LRIF1
MAN2A2
NEK2
PAK3
PCLO
PDPK1
PFDN1
PLCG1
PMF1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
PTK2
PTPRZ1
PXN
RAN
RGS2
RIF1
SRC
SRRT
TAB1
TERF1
TGFB1I1
TRIB3
TXNDC9
WDR33
YWHAG
Entrez ID
3163
28964
HPRD ID
00783
06577
Ensembl ID
ENSG00000103415
ENSG00000108262
Uniprot IDs
A0A087WT44
B3KSE0
P30519
Q59FC3
Q9Y2X7
PDB IDs
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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