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HMOX2 and MED31
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
HMOX2
MED31
Description
heme oxygenase 2
mediator complex subunit 31
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
Ubiquitin Ligase Complex
Nucleoplasm
Mediator Complex
Core Mediator Complex
Molecular Function
Heme Oxygenase (decyclizing) Activity
Protein Binding
Heme Binding
Metal Ion Binding
Transcription Coregulator Activity
Protein Binding
Ubiquitin Protein Ligase Activity
Biological Process
Response To Hypoxia
Heme Oxidation
Cellular Iron Ion Homeostasis
Response To Oxidative Stress
Heme Catabolic Process
Neutrophil Degranulation
Iron Ion Homeostasis
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Protein Ubiquitination
Negative Regulation Of Fibroblast Proliferation
Limb Development
Pathways
Heme degradation
Neutrophil degranulation
Iron uptake and transport
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction (
31806883
)
Interacting Genes
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ELOVL5
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LMNA
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
59 interacting genes:
AGR2
ANXA7
ASCC2
CACNB4
CCT7
CDKN1A
CPE
DAZAP2
DLEU1
DNM1
EEF1G
EGR2
EPN1
ERH
FAM118B
GADD45G
GSTM4
HGH1
HMOX2
HNRNPUL1
HSPB1
HSPB3
HTT
LAMA4
LYPLA2
MAFG
MED18
MED19
MED7
MED8
MED9
MOB4
NAF1
NFATC2
NR4A1
ORAI2
PABPC4
PAFAH1B3
PFDN1
PMF1
PQBP1
PRMT1
PSMD11
RAB25
RBM23
RFC5
RPA2
SAT1
SELENBP1
SERPINB9
SMN1
TGIF1
TINAGL1
TK1
TLE5
UBE2B
WDCP
ZBTB45
ZSCAN1
Entrez ID
3163
51003
HPRD ID
00783
14382
Ensembl ID
ENSG00000103415
ENSG00000108590
Uniprot IDs
A0A087WT44
B3KSE0
P30519
Q9Y3C7
PDB IDs
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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