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HMOX2 and ZFP28
Data Source:
BioGRID
(two hybrid)
HMOX2
ZFP28
Description
heme oxygenase 2
ZFP28 zinc finger protein
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
Nucleus
Molecular Function
Heme Oxygenase (decyclizing) Activity
Protein Binding
Heme Binding
Metal Ion Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Metal Ion Binding
Biological Process
Response To Hypoxia
Heme Oxidation
Cellular Iron Ion Homeostasis
Response To Oxidative Stress
Heme Catabolic Process
Neutrophil Degranulation
Iron Ion Homeostasis
Regulation Of Transcription By RNA Polymerase II
Pathways
Heme degradation
Neutrophil degranulation
Iron uptake and transport
Generic Transcription Pathway
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
Apolipoprotein B levels (
32203549
)
Interacting Genes
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ELOVL5
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LMNA
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
5 interacting genes:
C8orf33
HMOX2
KDM1A
PPP2CB
PRKRA
Entrez ID
3163
140612
HPRD ID
00783
15725
Ensembl ID
ENSG00000103415
ENSG00000196867
Uniprot IDs
A0A087WT44
B3KSE0
P30519
Q8NHY6
PDB IDs
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
2EM2
2EM3
2EM4
2EMJ
2EMK
2EML
2EN9
2ENH
2EOH
2EP0
2EPX
2EPZ
2YTM
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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