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GIT1 and HAP1
Data Source:
HPRD
(two hybrid, in vitro)
GIT1
HAP1
Description
GIT ArfGAP 1
huntingtin associated protein 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Cytosol
Focal Adhesion
Membrane
Calyx Of Held
Nucleolus
Mitochondrion
Lysosome
Early Endosome
Autophagosome
Endoplasmic Reticulum
Centrosome
Centriole
Cytosol
Cytoskeleton
Synaptic Vesicle
Actin Cytoskeleton
Inclusion Body
Dendrite
Growth Cone
Cytoplasmic Vesicle
Dendritic Spine
Axon Cytoplasm
Molecular Function
GTPase Activator Activity
Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Signaling Receptor Binding
Protein Binding
Myosin Binding
Ion Channel Binding
Brain-derived Neurotrophic Factor Binding
Biological Process
Intramembranous Ossification
Brain Development
Locomotory Behavior
Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Cytokinesis
Negative Regulation Of Interleukin-1 Beta Production
Positive Regulation Of GTPase Activity
Cell Redox Homeostasis
Negative Regulation Of Glycolytic Process
Ephrin Receptor Signaling Pathway
Neuron Development
Motor Learning
Cellular Response To Lipopolysaccharide
Presynaptic Modulation Of Chemical Synaptic Transmission
Negative Regulation Of Inflammatory Response To Wounding
Regulation Of Synaptic Vesicle Exocytosis
Protein Targeting
Exocytosis
Autophagy
Chemical Synaptic Transmission
Brain Development
Anterograde Axonal Transport
Retrograde Axonal Transport
Protein Localization
Regulation Of Exocytosis
Cerebellum Development
Hypothalamus Cell Differentiation
Neurogenesis
Cell Projection Organization
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Positive Regulation Of Synaptic Transmission, GABAergic
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Vesicle Transport Along Microtubule
Neurotrophin TRK Receptor Signaling Pathway
Mitochondrion Distribution
Positive Regulation Of Neurogenesis
Anterograde Axonal Transport Of Mitochondrion
Negative Regulation Of Amyloid-beta Formation
Regulation Of Organelle Transport Along Microtubule
Positive Regulation Of Non-motile Cilium Assembly
Pathways
Ephrin signaling
Ephrin signaling
Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Developmental language disorder (syntactic complexity) (
27016271
)
Esophageal cancer (squamous cell) (
22960999
)
Interacting Genes
52 interacting genes:
ARHGEF6
ARHGEF7
BARD1
C8orf33
CCDC113
CDC42
CENPU
CEP126
CHD3
DDX24
EIF6
ENTR1
GIT2
GRB2
GRK2
GRK3
GRK5
GRK6
HAP1
HMOX2
HTT
KIF1A
LAMTOR5
LPXN
LRIF1
MAN2A2
NEK2
PAK3
PCLO
PDPK1
PFDN1
PLCG1
PMF1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
PTK2
PTPRZ1
PXN
RAN
RGS2
RIF1
SRC
SRRT
TAB1
TERF1
TGFB1I1
TRIB3
TXNDC9
WDR33
YWHAG
93 interacting genes:
AEN
ANTKMT
APLP1
ATP5MF
BARD1
BRD7
C1orf216
C2CD6
C7orf25
C8orf33
CBX8
CCDC113
CCDC13
CDC73
CDK18
CDK5RAP2
COL9A2
CRIP1
DCTN1
DDX49
DEFB1
EIF3E
FAM50B
FEZ1
GABARAPL2
GADD45G
GIT1
GPRASP2
HDAC4
HGS
HMOX2
HOXB5
HSPA1A
HSPA4
HTT
IMMT
ING5
KAT5
KAT7
KATNBL1
KBTBD7
KPNA2
LRIF1
LUC7L2
MPP3
MRPS9
MSGN1
NAP1L5
NDUFB9
NEUROD1
NIPSNAP3A
NOD2
NOP53
PABPC4
PCM1
PDCD7
PFDN1
PKN1
PPID
PPOX
PPP1R18
PRPF31
PSMD11
RER1
RHPN1
RIF1
RPS10
RPS25
SCNM1
SNAPIN
SRSF4
STX5
TAF1D
TBP
TIMM17A
TNNT1
TNNT3
TOMM20
TSPYL1
UTP3
VIM
ZFP1
ZMAT2
ZNF124
ZNF20
ZNF24
ZNF33B
ZNF490
ZNF572
ZNF575
ZNF648
ZNF691
ZNF835
Entrez ID
28964
9001
HPRD ID
06577
02972
Ensembl ID
ENSG00000108262
ENSG00000173805
Uniprot IDs
Q59FC3
Q9Y2X7
P54257
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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