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HMOX2 and JADE1
Data Source:
BioGRID
(two hybrid)
HMOX2
JADE1
Description
heme oxygenase 2
jade family PHD finger 1
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Plasma Membrane
Nuclear Speck
Ciliary Basal Body
Molecular Function
Heme Oxygenase (decyclizing) Activity
Protein Binding
Heme Binding
Metal Ion Binding
Transcription Coactivator Activity
Protein Binding
Metal Ion Binding
Biological Process
Response To Hypoxia
Heme Oxidation
Cellular Iron Ion Homeostasis
Response To Oxidative Stress
Heme Catabolic Process
Neutrophil Degranulation
Iron Ion Homeostasis
Apoptotic Process
Negative Regulation Of Cell Growth
Histone H3 Acetylation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K12 Acetylation
Histone H4-K16 Acetylation
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Heme degradation
Neutrophil degranulation
Iron uptake and transport
HATs acetylate histones
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
Arterial stiffness index (
31235810
)
Bone mineral density (total hip) (
29883787
)
Interacting Genes
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ELOVL5
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LMNA
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
15 interacting genes:
AKT1
CTNNB1
H3C14
H4C1
HMOX2
PFDN1
SEPTIN8
SMN1
TK1
UBE2E1
UBE2H
UBE3A
VHL
YJU2
ZNF148
Entrez ID
3163
79960
HPRD ID
00783
10151
Ensembl ID
ENSG00000103415
ENSG00000077684
Uniprot IDs
A0A087WT44
B3KSE0
P30519
B4E2E2
Q6IE81
PDB IDs
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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