HMOX2 and SNX7

Data Source:
BioGRID (two hybrid)

		HMOX2	SNX7
Description		heme oxygenase 2	sorting nexin 7
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Cytoplasmic Vesicle Membrane
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding	Protein Binding Phosphatidylinositol Binding
	Biological Process	Response To Hypoxia Heme Oxidation Cellular Iron Ion Homeostasis Response To Oxidative Stress Heme Catabolic Process Neutrophil Degranulation Iron Ion Homeostasis	Protein Transport
Pathways		Heme degradation Neutrophil degranulation Iron uptake and transport
Drugs		NADH Stannsoporfin
Diseases
GWAS		Erectile dysfunction ( 30583798)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Copper levels ( 26025379) Dental caries ( 23259602) Disease progression in age-related macular degeneration ( 29346644) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General risk tolerance (MTAG) ( 30643258) Insulin-related traits (multivariate analysis) ( 32002517) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Methadone dose in opioid dependence ( 28115739) Night sleep phenotypes ( 27126917) Proinsulin levels ( 21873549) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097 31123309)
Interacting Genes		67 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ELOVL5 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LMNA LRIF1 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746	10 interacting genes: ABI2 BIRC3 HGS HMOX2 MAGEA11 MESD POLR2L SNX4 TBC1D21 TEX11
Entrez ID		3163	51375
HPRD ID		00783	15416
Ensembl ID		ENSG00000103415	ENSG00000162627
Uniprot IDs		A0A087WT44 B3KSE0 P30519	B4DP69 E9PNL2 Q9UNH6
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA	3IQ2
Enriched GO Terms of Interacting Partners?
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