HMOX2 and RNASEK

Data Source:
BioGRID (two hybrid)

		HMOX2	RNASEK
Description		heme oxygenase 2	ribonuclease K
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Cellular_component Integral Component Of Membrane
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding	Endoribonuclease Activity Protein Binding
	Biological Process	Response To Hypoxia Heme Oxidation Cellular Iron Ion Homeostasis Response To Oxidative Stress Heme Catabolic Process Neutrophil Degranulation Iron Ion Homeostasis	RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Heme degradation Neutrophil degranulation Iron uptake and transport
Drugs		NADH Stannsoporfin
Diseases
GWAS		Erectile dysfunction ( 30583798)
Interacting Genes		67 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ELOVL5 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LMNA LRIF1 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746	26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21
Entrez ID		3163	440400
HPRD ID		00783	17568
Ensembl ID		ENSG00000103415	ENSG00000219200
Uniprot IDs		A0A087WT44 B3KSE0 P30519	Q6P5S7
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?
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