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HMOX2 and GET1
Data Source:
BioGRID
(two hybrid)
HMOX2
GET1
Description
heme oxygenase 2
guided entry of tail-anchored proteins factor 1
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Molecular Function
Heme Oxygenase (decyclizing) Activity
Protein Binding
Heme Binding
Metal Ion Binding
Protein Binding
Biological Process
Response To Hypoxia
Heme Oxidation
Cellular Iron Ion Homeostasis
Response To Oxidative Stress
Heme Catabolic Process
Neutrophil Degranulation
Iron Ion Homeostasis
Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Heme degradation
Neutrophil degranulation
Iron uptake and transport
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
Interacting Genes
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ELOVL5
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LMNA
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
28 interacting genes:
ABHD5
APOA2
APOL2
AQP1
CAMLG
CCL4L2
CD302
CD53
CLCN7
COMT
COX20
ERG28
HMOX2
HTATIP2
ORMDL3
PLPP4
PTPN9
RASGRP3
RTP2
SERP2
SLC35E3
SLC7A1
SPTSSA
STX2
TECR
TFRC
TM4SF19
TMEM42
Entrez ID
3163
7485
HPRD ID
00783
04224
Ensembl ID
ENSG00000103415
ENSG00000182093
Uniprot IDs
A0A087WT44
B3KSE0
P30519
O00258
PDB IDs
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
6SO5
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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