Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
HMOX2 and INPP5K
Data Source:
BioGRID
(two hybrid)
HMOX2
INPP5K
Description
heme oxygenase 2
inositol polyphosphate-5-phosphatase K
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
Ruffle
Nucleus
Cytoplasm
Endoplasmic Reticulum
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Ruffle Membrane
Neuron Projection
Perinuclear Region Of Cytoplasm
Molecular Function
Heme Oxygenase (decyclizing) Activity
Protein Binding
Heme Binding
Metal Ion Binding
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity
Inositol-polyphosphate 5-phosphatase Activity
Vasopressin Receptor Activity
Protein Binding
Inositol Bisphosphate Phosphatase Activity
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Phosphatidylinositol Trisphosphate Phosphatase Activity
Phosphatidylinositol Phosphate 5-phosphatase Activity
Lipid Phosphatase Activity
Inositol Trisphosphate Phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Biological Process
Response To Hypoxia
Heme Oxidation
Cellular Iron Ion Homeostasis
Response To Oxidative Stress
Heme Catabolic Process
Neutrophil Degranulation
Iron Ion Homeostasis
In Utero Embryonic Development
Negative Regulation Of Protein Phosphorylation
Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Phosphatidylinositol Biosynthetic Process
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Glucose Transmembrane Transport
Dephosphorylation
Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Cellular Response To Hormone Stimulus
Negative Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Dephosphorylation
Positive Regulation Of Urine Volume
Glucose Homeostasis
Negative Regulation Of MAP Kinase Activity
Negative Regulation By Host Of Viral Transcription
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Receptor Signaling Pathway
Inositol Phosphate Dephosphorylation
Phosphatidylinositol Dephosphorylation
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Calcium Ion Transport
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Localization To Plasma Membrane
Negative Regulation Of Protein Targeting To Membrane
Ruffle Assembly
Negative Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Renal Water Transport
Pathways
Heme degradation
Neutrophil degranulation
Iron uptake and transport
Synthesis of PIPs at the plasma membrane
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
Mean platelet volume (
27863252
)
Interacting Genes
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ELOVL5
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LMNA
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
23 interacting genes:
ANXA7
ARL6IP1
ATP5PF
BDNF
CDKN1A
CPTP
FADS6
FATE1
FBXO7
GOLT1B
HMOX2
HSPB1
KRT31
MAD2L1BP
NCOR2
PBX3
PFDN1
SFT2D2
SMN1
TANK
TK1
TNFRSF10D
TTR
Entrez ID
3163
51763
HPRD ID
00783
08489
Ensembl ID
ENSG00000103415
ENSG00000132376
Uniprot IDs
A0A087WT44
B3KSE0
P30519
B7Z4V9
Q9BT40
PDB IDs
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?