GIT1 and ENTR1

Data Source:
BioGRID (pull down, affinity chromatography technology, two hybrid, proximity labelling technology)
HPRD (two hybrid)

		GIT1	ENTR1
Description		GIT ArfGAP 1	endosome associated trafficking regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Focal Adhesion Membrane Calyx Of Held	Endosome Early Endosome Centrosome Midbody Retromer Complex Ciliary Basal Body Recycling Endosome
	Molecular Function	GTPase Activator Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding	Protein Binding
	Biological Process	Intramembranous Ossification Brain Development Locomotory Behavior Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Cytokinesis Negative Regulation Of Interleukin-1 Beta Production Positive Regulation Of GTPase Activity Cell Redox Homeostasis Negative Regulation Of Glycolytic Process Ephrin Receptor Signaling Pathway Neuron Development Motor Learning Cellular Response To Lipopolysaccharide Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Inflammatory Response To Wounding Regulation Of Synaptic Vesicle Exocytosis	Cell Cycle Protein Transport Cell Projection Organization Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Cell Division Positive Regulation Of Protein Localization To Cilium Retrograde Transport, Endosome To Plasma Membrane
Pathways		Ephrin signaling Ephrin signaling Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		52 interacting genes: ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CDC42 CENPU CEP126 CHD3 DDX24 EIF6 ENTR1 GIT2 GRB2 GRK2 GRK3 GRK5 GRK6 HAP1 HMOX2 HTT KIF1A LAMTOR5 LPXN LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG	13 interacting genes: AP1M1 APP AXIN1 CD99 CHD3 CSNK1E DDX6 GIT1 NOD2 SDCBP SMURF1 TFPT VIM
Entrez ID		28964	10807
HPRD ID		06577	15307
Ensembl ID		ENSG00000108262	ENSG00000165689
Uniprot IDs		Q59FC3 Q9Y2X7	Q96C92
PDB IDs
Enriched GO Terms of Interacting Partners?
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