GIT1 and TXNDC9

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GIT1	TXNDC9
Description		GIT ArfGAP 1	thioredoxin domain containing 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Focal Adhesion Membrane Calyx Of Held	Nucleus Centrosome Cytosol Midbody
	Molecular Function	GTPase Activator Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding	Protein Binding Cadherin Binding
	Biological Process	Intramembranous Ossification Brain Development Locomotory Behavior Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Cytokinesis Negative Regulation Of Interleukin-1 Beta Production Positive Regulation Of GTPase Activity Cell Redox Homeostasis Negative Regulation Of Glycolytic Process Ephrin Receptor Signaling Pathway Neuron Development Motor Learning Cellular Response To Lipopolysaccharide Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Inflammatory Response To Wounding Regulation Of Synaptic Vesicle Exocytosis	Biological_process
Pathways		Ephrin signaling Ephrin signaling Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain morphology (MOSTest) ( 32665545)	Bipolar disorder ( 21926972) Heel bone mineral density ( 30598549)
Interacting Genes		52 interacting genes: ARHGEF6 ARHGEF7 BARD1 C8orf33 CCDC113 CDC42 CENPU CEP126 CHD3 DDX24 EIF6 ENTR1 GIT2 GRB2 GRK2 GRK3 GRK5 GRK6 HAP1 HMOX2 HTT KIF1A LAMTOR5 LPXN LRIF1 MAN2A2 NEK2 PAK3 PCLO PDPK1 PFDN1 PLCG1 PMF1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PTK2 PTPRZ1 PXN RAN RGS2 RIF1 SRC SRRT TAB1 TERF1 TGFB1I1 TRIB3 TXNDC9 WDR33 YWHAG	27 interacting genes: C1orf94 C3orf62 CCDC172 CEP126 CEP76 CHD3 COG4 DYDC1 ELP1 EXOSC8 FEZ1 GIT1 IMMT KLF11 LZTS1 MAGEA6 MED22 MRPL12 MYOG PBX4 PICK1 PNMA1 PTN SETDB1 TEX9 TRIM27 ZNF655
Entrez ID		28964	10190
HPRD ID		06577	15592
Ensembl ID		ENSG00000108262	ENSG00000115514
Uniprot IDs		Q59FC3 Q9Y2X7	O14530
PDB IDs
Enriched GO Terms of Interacting Partners?
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