HMOX2 and ARL13B

Data Source:
BioGRID (two hybrid)

		HMOX2	ARL13B
Description		heme oxygenase 2	ADP ribosylation factor like GTPase 13B
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Cilium Motile Cilium Ciliary Membrane Non-motile Cilium
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding	Protein Binding GTP Binding
	Biological Process	Response To Hypoxia Heme Oxidation Cellular Iron Ion Homeostasis Response To Oxidative Stress Heme Catabolic Process Neutrophil Degranulation Iron Ion Homeostasis	Smoothened Signaling Pathway Neural Tube Patterning Interneuron Migration From The Subpallium To The Cortex Formation Of Radial Glial Scaffolds Cilium Assembly Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly
Pathways		Heme degradation Neutrophil degranulation Iron uptake and transport	ARL13B-mediated ciliary trafficking of INPP5E Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs		NADH Stannsoporfin
Diseases			Joubert syndrome
GWAS		Erectile dysfunction ( 30583798)
Interacting Genes		67 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ELOVL5 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LMNA LRIF1 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746	130 interacting genes: ACSF2 AIG1 ALG3 ANKRD46 AOC3 AQP10 B4GALNT2 BMP10 BNIP3 BRICD5 C1GALT1 C2CD2L C4orf3 CCDC167 CCL4 CCL4L2 CD151 CD302 CD53 CDIPT CFHR5 CLDN4 CLDN8 CLEC4G CLEC7A CLN6 CMTM3 CMTM7 COL8A2 CSGALNACT2 CTSA CXCL16 CYB561D2 EBP EMP1 ENTPD3 FAXDC2 FDFT1 FKBP8 FUNDC2 FXYD6 GAD2 GIMAP1 GIMAP5 GJB2 GOSR2 GPR37L1 HMOX1 HMOX2 HOMER3 ICMT ITGAM JAGN1 KCNJ2 KLRG1 LEPROTL1 LPAR3 MAL2 MALL MMD MOSPD3 MUCL1 MYADML2 NAT8 NINJ2 NKG7 NRM NUCB2 ORMDL1 ORMDL3 PAEP PDZK1IP1 PGAP2 PLN PLP1 PLPP4 PLPPR2 PMP22 PRB1 PTPN9 RTP2 S100A2 SACM1L SEMA4G SLC13A3 SLC2A5 SLC35A1 SLC35B1 SLC38A7 SLC39A2 SMAGP SPN STRIT1 STX1A STX7 TECR TEX264 TFRC THSD7A THSD7B TM6SF2 TMEM11 TMEM121 TMEM128 TMEM14C TMEM187 TMEM190 TMEM218 TMEM229B TMEM254 TMEM43 TMEM54 TMEM65 TMEM79 TMEM86B TMEM97 TMUB2 TNFRSF10C TNMD TRARG1 TSPO2 UBE2I VAMP1 VAMP2 VAMP3 VAMP4 VSTM1 WFDC2 YIPF6 ZDHHC15
Entrez ID		3163	200894
HPRD ID		00783	12334
Ensembl ID		ENSG00000103415	ENSG00000169379
Uniprot IDs		A0A087WT44 B3KSE0 P30519	Q3SXY8
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?
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