MED31 and TINAGL1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED31	TINAGL1
Description		mediator complex subunit 31	tubulointerstitial nephritis antigen like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex Core Mediator Complex	Extracellular Region Extracellular Space Lysosome Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	Extracellular Matrix Structural Constituent Protein Binding Cysteine-type Peptidase Activity Laminin Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Negative Regulation Of Fibroblast Proliferation Limb Development	Proteolysis Endosomal Transport
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Blood protein levels ( 30072576) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		59 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1	18 interacting genes: BAG4 CAPN1 EP300 KRTAP10-3 KRTAP12-2 KRTAP4-2 LMO4 MDFI MED31 MTDH NOTCH2NLA PITX2 PROP1 RBPMS SHBG SMAD9 TRIP13 UTP14A
Entrez ID		51003	64129
HPRD ID		14382	07122
Ensembl ID		ENSG00000108590	ENSG00000142910
Uniprot IDs		Q9Y3C7	F6SDV2 Q9GZM7
PDB IDs
Enriched GO Terms of Interacting Partners?
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