SNX7 and SNX4

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SNX7	SNX4
Description		sorting nexin 7	sorting nexin 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle Membrane	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane SNARE Complex Early Endosome Membrane Protein-containing Complex
	Molecular Function	Protein Binding Phosphatidylinositol Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Protein Transport	Protein Transport Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Copper levels ( 26025379) Dental caries ( 23259602) Disease progression in age-related macular degeneration ( 29346644) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General risk tolerance (MTAG) ( 30643258) Insulin-related traits (multivariate analysis) ( 32002517) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Methadone dose in opioid dependence ( 28115739) Night sleep phenotypes ( 27126917) Proinsulin levels ( 21873549) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097 31123309)	Adult body size ( 32376654) Estimated glomerular filtration rate in non-diabetics ( 31451708) Urate levels ( 31578528)
Interacting Genes		10 interacting genes: ABI2 BIRC3 HGS HMOX2 MAGEA11 MESD POLR2L SNX4 TBC1D21 TEX11	18 interacting genes: AGK ARL6IP1 ATP6V0A1 BIN1 DGAT2L6 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SH3GLB1 SNX2 SNX6 SNX7 SUPT5H
Entrez ID		51375	8723
HPRD ID		15416	09334
Ensembl ID		ENSG00000162627	ENSG00000114520
Uniprot IDs		B4DP69 E9PNL2 Q9UNH6	O95219
PDB IDs		3IQ2
Enriched GO Terms of Interacting Partners?
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