VDAC2 and DUX4

Data Source:
BioGRID (pull down)

		VDAC2	DUX4
Description		voltage dependent anion channel 2	double homeobox 4
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Mitochondrion Mitochondrial Outer Membrane Synaptic Vesicle Membrane Mitochondrial Membrane Mitochondrial Nucleoid Pore Complex	Nucleus Nucleoplasm Nucleolus Golgi Apparatus Cytosol Nuclear Membrane
	Molecular Function	Nucleotide Binding Protein Binding Voltage-gated Anion Channel Activity Porin Activity Cholesterol Binding Phosphatidylcholine Binding Ceramide Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Anion Transport Binding Of Sperm To Zona Pellucida Inorganic Anion Transport Negative Regulation Of Protein Polymerization Mitochondrial Outer Membrane Permeabilization Anion Transmembrane Transport Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Multicellular Organism Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways		Ub-specific processing proteases Mitochondrial calcium ion transport
Drugs		Aluminium monostearate PRLX 93936
Diseases
GWAS
Interacting Genes		11 interacting genes: ADRB2 APP BAK1 CYCS DUX4 DUX4L9 ECT2 HK1 NEDD4 NEDD4L RPS3A	124 interacting genes: ACTG1 AP2A1 AP3D1 ARF1 ATP5F1C C1QBP CAND1 CAPN2 CAVIN1 CCT6A CLTC COPA CSE1L DDX21 DDX3X DDX5 DES DHX30 DHX36 DHX9 DYNC1H1 EEF2 EFTUD2 ENO1 EP300 EPRS1 FASN FLNA GAPDH GARS1 HMGB1 HNRNPA1L2 HNRNPF HNRNPH1 HNRNPK HNRNPM HNRNPU HSPD1 IARS1 IGF2BP1 IGF2BP3 ILF3 IQGAP1 LDHA MARS1 MCM7 MTHFD1 MYBBP1A MYH10 MYH9 MYL6B NCL NPM1 PABPC1 PABPC4 PARP1 PFAS PKM PPP2R1A PRKDC PRPF8 RAN RPL10 RPL10A RPL12 RPL13 RPL15 RPL17 RPL18 RPL19 RPL21 RPL22 RPL23 RPL23A RPL27A RPL3 RPL30 RPL31 RPL35 RPL36 RPL4 RPL6 RPL7 RPL7A RPL8 RPL9 RPN1 RPS10 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS2 RPS20 RPS24 RPS25 RPS3 RPS3A RPS4X RPS6 RPS7 RPS8 RPS9 SF3B1 SHMT2 SLC25A3 SLC25A5 SLC25A6 SNRNP200 SRSF3 TCP1 TUBB TUBB2A TUBB3 TUBB6 VDAC1 VDAC2 VIM XRCC5 XRCC6 YBX1
Entrez ID		7417	100288687
HPRD ID		01904
Ensembl ID		ENSG00000165637	ENSG00000260596
Uniprot IDs		A0A024QZT0 B4DKM5 P45880	C3U3A0 Q9UBX2
PDB IDs			5Z2S 5Z2T 5Z6Z 5ZFW 5ZFY 5ZFZ 6A8R 6DFY 6E8C 6U81 6U82
Enriched GO Terms of Interacting Partners?
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