Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
DUX4 and EEF2
Data Source:
BioGRID
(pull down)
DUX4
EEF2
Description
double homeobox 4
eukaryotic translation elongation factor 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Golgi Apparatus
Cytosol
Nuclear Membrane
Extracellular Region
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aggresome
Secretory Granule Lumen
Polysomal Ribosome
Membrane Raft
Synapse
Extracellular Exosome
Ficolin-1-rich Granule Lumen
Ribonucleoprotein Complex
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
P53 Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
GTP Binding
5S RRNA Binding
Protein Kinase Binding
Ribosome Binding
Cadherin Binding
Actin Filament Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Multicellular Organism Development
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of G0 To G1 Transition
Hematopoietic Progenitor Cell Differentiation
Response To Ischemia
Skeletal Muscle Contraction
Translational Elongation
Aging
Glial Cell Proliferation
Response To Estradiol
Response To Endoplasmic Reticulum Stress
Skeletal Muscle Cell Differentiation
Response To Drug
Response To Hydrogen Peroxide
Neutrophil Degranulation
Response To Ethanol
Positive Regulation Of Translation
Response To Folic Acid
Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Positive Regulation Of Cytoplasmic Translation
Pathways
Peptide chain elongation
Peptide chain elongation
Uptake and function of diphtheria toxin
Synthesis of diphthamide-EEF2
Synthesis of diphthamide-EEF2
Neutrophil degranulation
Protein methylation
Drugs
Adenosine-5-Diphosphoribose
Diphthamide
Guanosine-5'-Diphosphate
N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
Esketamine
Moxetumomab Pasudotox
Diseases
GWAS
Interacting Genes
124 interacting genes:
ACTG1
AP2A1
AP3D1
ARF1
ATP5F1C
C1QBP
CAND1
CAPN2
CAVIN1
CCT6A
CLTC
COPA
CSE1L
DDX21
DDX3X
DDX5
DES
DHX30
DHX36
DHX9
DYNC1H1
EEF2
EFTUD2
ENO1
EP300
EPRS1
FASN
FLNA
GAPDH
GARS1
HMGB1
HNRNPA1L2
HNRNPF
HNRNPH1
HNRNPK
HNRNPM
HNRNPU
HSPD1
IARS1
IGF2BP1
IGF2BP3
ILF3
IQGAP1
LDHA
MARS1
MCM7
MTHFD1
MYBBP1A
MYH10
MYH9
MYL6B
NCL
NPM1
PABPC1
PABPC4
PARP1
PFAS
PKM
PPP2R1A
PRKDC
PRPF8
RAN
RPL10
RPL10A
RPL12
RPL13
RPL15
RPL17
RPL18
RPL19
RPL21
RPL22
RPL23
RPL23A
RPL27A
RPL3
RPL30
RPL31
RPL35
RPL36
RPL4
RPL6
RPL7
RPL7A
RPL8
RPL9
RPN1
RPS10
RPS13
RPS14
RPS15
RPS15A
RPS16
RPS17
RPS18
RPS2
RPS20
RPS24
RPS25
RPS3
RPS3A
RPS4X
RPS6
RPS7
RPS8
RPS9
SF3B1
SHMT2
SLC25A3
SLC25A5
SLC25A6
SNRNP200
SRSF3
TCP1
TUBB
TUBB2A
TUBB3
TUBB6
VDAC1
VDAC2
VIM
XRCC5
XRCC6
YBX1
21 interacting genes:
CCT2
CDKN2A
DISC1
DUX4
EEF2K
EP300
ESR1
HNRNPD
LINC01554
MAPKAPK3
MLH1
NDRG1
PPM1A
PPP2CA
PPP2R1A
PPP2R1B
PTEN
SUMO2
TP53
TRPM7
UCHL5
Entrez ID
100288687
1938
HPRD ID
00561
Ensembl ID
ENSG00000260596
ENSG00000167658
Uniprot IDs
C3U3A0
Q9UBX2
A0A384N6H1
P13639
PDB IDs
5Z2S
5Z2T
5Z6Z
5ZFW
5ZFY
5ZFZ
6A8R
6DFY
6E8C
6U81
6U82
4V6X
6D9J
6Z6M
6Z6N
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?