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DUX4 and LDHA
Data Source:
BioGRID
(pull down)
DUX4
LDHA
Description
double homeobox 4
lactate dehydrogenase A
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Golgi Apparatus
Cytosol
Nuclear Membrane
Nucleus
Cytosol
Membrane
Extracellular Exosome
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
L-lactate Dehydrogenase Activity
Protein Binding
Kinase Binding
Identical Protein Binding
Cadherin Binding
NAD Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Multicellular Organism Development
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of G0 To G1 Transition
Response To Hypoxia
Lactate Metabolic Process
Pyruvate Metabolic Process
Glycolytic Process
Response To Nutrient
Response To Glucose
NAD Metabolic Process
Response To Drug
Response To Hydrogen Peroxide
Positive Regulation Of Apoptotic Process
Response To Estrogen
Post-embryonic Animal Organ Development
Response To CAMP
Pathways
Pyruvate metabolism
Drugs
NADH
Etheno-NAD
Nicotinamide
Oxamic Acid
Stiripentol
Copper
Artenimol
Diseases
GWAS
Amyloid A serum levels (
21124955
)
Interacting Genes
124 interacting genes:
ACTG1
AP2A1
AP3D1
ARF1
ATP5F1C
C1QBP
CAND1
CAPN2
CAVIN1
CCT6A
CLTC
COPA
CSE1L
DDX21
DDX3X
DDX5
DES
DHX30
DHX36
DHX9
DYNC1H1
EEF2
EFTUD2
ENO1
EP300
EPRS1
FASN
FLNA
GAPDH
GARS1
HMGB1
HNRNPA1L2
HNRNPF
HNRNPH1
HNRNPK
HNRNPM
HNRNPU
HSPD1
IARS1
IGF2BP1
IGF2BP3
ILF3
IQGAP1
LDHA
MARS1
MCM7
MTHFD1
MYBBP1A
MYH10
MYH9
MYL6B
NCL
NPM1
PABPC1
PABPC4
PARP1
PFAS
PKM
PPP2R1A
PRKDC
PRPF8
RAN
RPL10
RPL10A
RPL12
RPL13
RPL15
RPL17
RPL18
RPL19
RPL21
RPL22
RPL23
RPL23A
RPL27A
RPL3
RPL30
RPL31
RPL35
RPL36
RPL4
RPL6
RPL7
RPL7A
RPL8
RPL9
RPN1
RPS10
RPS13
RPS14
RPS15
RPS15A
RPS16
RPS17
RPS18
RPS2
RPS20
RPS24
RPS25
RPS3
RPS3A
RPS4X
RPS6
RPS7
RPS8
RPS9
SF3B1
SHMT2
SLC25A3
SLC25A5
SLC25A6
SNRNP200
SRSF3
TCP1
TUBB
TUBB2A
TUBB3
TUBB6
VDAC1
VDAC2
VIM
XRCC5
XRCC6
YBX1
19 interacting genes:
ABCC9
ACD
DUX4
DYNLL1
FGFR1
HNRNPD
HULC
KCNJ11
LDHB
MAPK10
NDRG1
PCNA
POT1
PTPRF
TERF1
TINF2
UPF2
XRN1
YWHAQ
Entrez ID
100288687
3939
HPRD ID
01025
Ensembl ID
ENSG00000260596
ENSG00000134333
Uniprot IDs
C3U3A0
Q9UBX2
P00338
V9HWB9
PDB IDs
5Z2S
5Z2T
5Z6Z
5ZFW
5ZFY
5ZFZ
6A8R
6DFY
6E8C
6U81
6U82
1I10
4AJP
4JNK
4L4R
4L4S
4M49
4OJN
4OKN
4QO7
4QO8
4QSM
4QT0
4R68
4R69
4RLS
4ZVV
5IXS
5IXY
5W8H
5W8I
5W8J
5W8K
5W8L
5ZJD
5ZJE
5ZJF
6BAD
6BAG
6BAX
6BAZ
6BB0
6BB1
6BB2
6BB3
6MV8
6MVA
6Q0D
6Q13
6SBU
6SBV
6ZZR
Enriched GO Terms of Interacting Partners
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