VDAC2 and RPS3A

Data Source:
HPRD (in vitro)

		VDAC2	RPS3A
Description		voltage dependent anion channel 2	ribosomal protein S3A
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Mitochondrion Mitochondrial Outer Membrane Synaptic Vesicle Membrane Mitochondrial Membrane Mitochondrial Nucleoid Pore Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Cytosolic Small Ribosomal Subunit Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding Protein Binding Voltage-gated Anion Channel Activity Porin Activity Cholesterol Binding Phosphatidylcholine Binding Ceramide Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding
	Biological Process	Anion Transport Binding Of Sperm To Zona Pellucida Inorganic Anion Transport Negative Regulation Of Protein Polymerization Mitochondrial Outer Membrane Permeabilization Anion Transmembrane Transport Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Cell Differentiation Negative Regulation Of Apoptotic Process
Pathways		Ub-specific processing proteases Mitochondrial calcium ion transport	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Aluminium monostearate PRLX 93936
Diseases
GWAS			HDL cholesterol ( 20686565)
Interacting Genes		11 interacting genes: ADRB2 APP BAK1 CYCS DUX4 DUX4L9 ECT2 HK1 NEDD4 NEDD4L RPS3A	18 interacting genes: ATF7IP C11orf49 CCDC50 CHN1 CREB3 DDIT3 DUX4 EDEM2 FANCC HGS HSP90AA1 NEDD4 PARP1 SAP18 SOD2 TOE1 UBE2I VDAC2
Entrez ID		7417	6189
HPRD ID		01904	01606
Ensembl ID		ENSG00000165637	ENSG00000145425
Uniprot IDs		A0A024QZT0 B4DKM5 P45880	B7Z3M5 P61247
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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