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DUX4 and VDAC2
Data Source:
BioGRID
(pull down)
DUX4
VDAC2
Description
double homeobox 4
voltage dependent anion channel 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Golgi Apparatus
Cytosol
Nuclear Membrane
Acrosomal Vesicle
Nucleus
Mitochondrion
Mitochondrial Outer Membrane
Synaptic Vesicle
Membrane
Mitochondrial Membrane
Mitochondrial Nucleoid
Pore Complex
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Nucleotide Binding
Protein Binding
Voltage-gated Anion Channel Activity
Porin Activity
Cholesterol Binding
Phosphatidylcholine Binding
Ceramide Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Multicellular Organism Development
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of G0 To G1 Transition
Anion Transport
Binding Of Sperm To Zona Pellucida
Inorganic Anion Transport
Negative Regulation Of Protein Polymerization
Mitochondrial Outer Membrane Permeabilization
Anion Transmembrane Transport
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Ub-specific processing proteases
Mitochondrial calcium ion transport
Drugs
Aluminium monostearate
PRLX 93936
Diseases
GWAS
Interacting Genes
124 interacting genes:
ACTG1
AP2A1
AP3D1
ARF1
ATP5F1C
C1QBP
CAND1
CAPN2
CAVIN1
CCT6A
CLTC
COPA
CSE1L
DDX21
DDX3X
DDX5
DES
DHX30
DHX36
DHX9
DYNC1H1
EEF2
EFTUD2
ENO1
EP300
EPRS1
FASN
FLNA
GAPDH
GARS1
HMGB1
HNRNPA1L2
HNRNPF
HNRNPH1
HNRNPK
HNRNPM
HNRNPU
HSPD1
IARS1
IGF2BP1
IGF2BP3
ILF3
IQGAP1
LDHA
MARS1
MCM7
MTHFD1
MYBBP1A
MYH10
MYH9
MYL6B
NCL
NPM1
PABPC1
PABPC4
PARP1
PFAS
PKM
PPP2R1A
PRKDC
PRPF8
RAN
RPL10
RPL10A
RPL12
RPL13
RPL15
RPL17
RPL18
RPL19
RPL21
RPL22
RPL23
RPL23A
RPL27A
RPL3
RPL30
RPL31
RPL35
RPL36
RPL4
RPL6
RPL7
RPL7A
RPL8
RPL9
RPN1
RPS10
RPS13
RPS14
RPS15
RPS15A
RPS16
RPS17
RPS18
RPS2
RPS20
RPS24
RPS25
RPS3
RPS3A
RPS4X
RPS6
RPS7
RPS8
RPS9
SF3B1
SHMT2
SLC25A3
SLC25A5
SLC25A6
SNRNP200
SRSF3
TCP1
TUBB
TUBB2A
TUBB3
TUBB6
VDAC1
VDAC2
VIM
XRCC5
XRCC6
YBX1
11 interacting genes:
ADRB2
APP
BAK1
CYCS
DUX4
DUX4L9
ECT2
HK1
NEDD4
NEDD4L
RPS3A
Entrez ID
100288687
7417
HPRD ID
01904
Ensembl ID
ENSG00000260596
ENSG00000165637
Uniprot IDs
C3U3A0
Q9UBX2
A0A024QZT0
B4DKM5
P45880
PDB IDs
5Z2S
5Z2T
5Z6Z
5ZFW
5ZFY
5ZFZ
6A8R
6DFY
6E8C
6U81
6U82
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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