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MBD3 and MKRN3
Data Source:
BioGRID
(two hybrid)
MBD3
MKRN3
Description
methyl-CpG binding domain protein 3
makorin ring finger protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleoplasm
Cytoplasm
NuRD Complex
Protein-containing Complex
Ribonucleoprotein Complex
Molecular Function
DNA Binding
Protein Binding
Methyl-CpG Binding
Nucleosomal DNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
DNA Methylation-dependent Heterochromatin Assembly
Brain Development
Heart Development
Aging
Tissue Development
Histone Acetylation
Response To Nutrient Levels
Response To Estradiol
ATP-dependent Chromatin Remodeling
Regulation Of DNA Methylation
Embryonic Organ Development
Regulation Of Signal Transduction By P53 Class Mediator
Protein Polyubiquitination
Protein Ubiquitination
Pathways
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Height (
31562340
)
Menarche (age at onset) (
25231870
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Interacting Genes
76 interacting genes:
AGR2
ANKRD33
ASCL4
ATF7
AURKA
BCL11B
CCDC183
CCHCR1
CCNC
CENPP
CEP70
CEP76
CT55
ERCC6
EXOC4
FAM136A
GADD45GIP1
GATAD2A
GATAD2B
GOLGA2
GOLGA6L9
H3-4
HDAC1
ICA1
IGFBP6
IK
JUN
KDM1A
KDM5B
KRT15
KRT16
LDOC1
LMO3
MAGEA2
MAGEA2B
MBD2
MBD3L1
MBD3L2
MECOM
MEIS3
MEOX1
MEOX2
MIPOL1
MKRN3
MTA2
MTUS2
MYOG
NUTM1
PBX4
PDGFA
PFDN6
PICK1
PKNOX2
PRKAR1B
RAB3IP
RBBP4
RBBP7
RCN3
REL
RINT1
SDCBP
SERTAD3
SMARCA4
SPEN
STMN2
SYCE1
TBC1D19
TET1
TIMM10B
TNNI1
TRIM54
TTC23
USP11
ZBTB7A
ZNF277
ZNF655
178 interacting genes:
ACOT11
ADAMTSL4
ADRA2C
ANKRD11
ANTKMT
APEX2
AQP1
ARID5A
ARMC5
AVPI1
BATF2
BCL2L11
BEX2
BLZF1
BPIFA1
C10orf82
C21orf58
CCDC120
CCDC185
CCDC187
CCDC33
CDCA4
CEP70
CERCAM
CRACR2A
CYSRT1
DDIT4L
ECM1
ECSIT
EFEMP1
ENKD1
ERCC1
FAM110A
FAM124B
FAM214B
FARS2
GADD45GIP1
GATA1
GEM
GOLGA6A
GRAP2
HCK
HGS
HOXA1
HOXD12
HSF2BP
HSF4
IGF1
IKZF3
INO80B
KANK2
KIF1A
KIFC3
KLF1
KLHL38
KRT34
KRT75
KRT86
KRTAP19-2
KRTAP19-6
KRTAP19-7
KRTAP21-2
KRTAP6-2
KRTAP7-1
KRTAP8-1
LAGE3
LASP1
LRSAM1
MAGED1
MBD3
MCCD1
MDM2
MDM4
MEOX1
MEOX2
MGAT5B
MIF4GD
MNAT1
MORN3
MRPL38
MRPS6
MYOZ2
NABP1
NDE1
NDUFB7
NKAPD1
NME4
ODAD4
ODF3B
PEX10
PEX5
PKN1
POLR1C
POMC
PRKAA2
PRPF31
PRR22
PRR35
PSMA1
PSMB1
PTH1R
PTK6
RASD1
RBM41
RBPMS
RBPMS2
RIBC1
RNF166
RNF32
RNF7
RSPO4
RTP5
SCNM1
SF1
SFN
SLPI
SMARCD1
SMYD3
SNRPC
SORBS3
SPATA8
STH
STMN3
STN1
SYNGAP1
TADA2A
TASOR2
TCEA2
TCHP
TCL1B
TENT5B
TFAP2A
TFIP11
TLE5
TPRX1
TRAF2
TRIM23
TRIM31
TRIM34
TRIM5
TRIM65
TRIM8
TSG101
TSGA10IP
TSPAN4
TTC23
TXNDC11
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2K
UBE2L3
UBE2N
UBE2U
UBE2V1
UBE2V2
UBE2W
UQCC2
USHBP1
VPS9D1
WDR25
WWOX
YPEL3
ZBTB42
ZFC3H1
ZFP57
ZIM2
ZNF34
ZNF414
ZNF587
ZNF688
ZNF835
Entrez ID
53615
7681
HPRD ID
04653
04836
Ensembl ID
ENSG00000071655
ENSG00000179455
Uniprot IDs
O95983
Q13064
PDB IDs
2MB7
6CC8
6CCG
6CEU
6CEV
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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