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MBD3 and PRKAR1B
Data Source:
BioGRID
(two hybrid)
MBD3
PRKAR1B
Description
methyl-CpG binding domain protein 3
protein kinase cAMP-dependent type I regulatory subunit beta
Image
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleoplasm
Cytoplasm
NuRD Complex
Protein-containing Complex
Multivesicular Body
Cytosol
Plasma Membrane
CAMP-dependent Protein Kinase Complex
Ciliary Base
Schaffer Collateral - CA1 Synapse
Hippocampal Mossy Fiber To CA3 Synapse
Glutamatergic Synapse
Molecular Function
DNA Binding
Protein Binding
Methyl-CpG Binding
Nucleosomal DNA Binding
CAMP-dependent Protein Kinase Inhibitor Activity
Protein Binding
CAMP-dependent Protein Kinase Regulator Activity
CAMP Binding
Protein Kinase A Catalytic Subunit Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
DNA Methylation-dependent Heterochromatin Assembly
Brain Development
Heart Development
Aging
Tissue Development
Histone Acetylation
Response To Nutrient Levels
Response To Estradiol
ATP-dependent Chromatin Remodeling
Regulation Of DNA Methylation
Embryonic Organ Development
Regulation Of Signal Transduction By P53 Class Mediator
Renal Water Homeostasis
Protein Phosphorylation
Blood Coagulation
Learning Or Memory
Regulation Of Protein Kinase A Signaling
Activation Of Protein Kinase A Activity
Regulation Of CAMP-mediated Signaling
Modulation Of Chemical Synaptic Transmission
Cellular Response To Glucagon Stimulus
Regulation Of Synaptic Vesicle Cycle
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Vasopressin regulates renal water homeostasis via Aquaporins
CREB1 phosphorylation through the activation of Adenylate Cyclase
Hedgehog 'off' state
ADORA2B mediated anti-inflammatory cytokines production
FCGR3A-mediated IL10 synthesis
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Body size at age 10 (
32376654
)
Hematocrit (
32888494
27863252
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Plasma free amino acid levels (
30659259
)
Red blood cell count (
32888494
27863252
)
Interacting Genes
76 interacting genes:
AGR2
ANKRD33
ASCL4
ATF7
AURKA
BCL11B
CCDC183
CCHCR1
CCNC
CENPP
CEP70
CEP76
CT55
ERCC6
EXOC4
FAM136A
GADD45GIP1
GATAD2A
GATAD2B
GOLGA2
GOLGA6L9
H3-4
HDAC1
ICA1
IGFBP6
IK
JUN
KDM1A
KDM5B
KRT15
KRT16
LDOC1
LMO3
MAGEA2
MAGEA2B
MBD2
MBD3L1
MBD3L2
MECOM
MEIS3
MEOX1
MEOX2
MIPOL1
MKRN3
MTA2
MTUS2
MYOG
NUTM1
PBX4
PDGFA
PFDN6
PICK1
PKNOX2
PRKAR1B
RAB3IP
RBBP4
RBBP7
RCN3
REL
RINT1
SDCBP
SERTAD3
SMARCA4
SPEN
STMN2
SYCE1
TBC1D19
TET1
TIMM10B
TNNI1
TRIM54
TTC23
USP11
ZBTB7A
ZNF277
ZNF655
76 interacting genes:
AKAP1
AKAP14
AKAP7
ANKS1A
BAG3
BAG6
BOD1L2
CAMSAP1
CBX8
CCDC103
CCDC187
CDC37
CDKN1A
CEP19
COX5B
DACH1
DTNB
EEF2KMT
EGFR
FAM161A
FAM90A1
FCHSD2
GAS2L2
GLIS2
GNL3L
GOLGA1
GPKOW
GUCA1A
IGFN1
INPP5J
KANK2
KIF5B
L3MBTL2
LENG1
LNX1
MBD3
MED8
MYO15B
NTAQ1
NXF1
PIK3R3
POLE4
PPP1R9A
PRKAA2
PRKACA
PRKAR1A
PRPF18
PSMG1
QRICH1
RARG
RUNX1T1
SAP30BP
SH2D4A
SHC3
SMAD3
SMAD4
SMG9
SNW1
STK16
SYTL4
TASOR2
TEAD4
THRA
TSGA10IP
UACA
VEZF1
WNK1
WRN
ZBTB16
ZMYND19
ZNF177
ZNF329
ZNF35
ZNF410
ZNF559-ZNF177
ZNF76
Entrez ID
53615
5575
HPRD ID
04653
01485
Ensembl ID
ENSG00000071655
ENSG00000188191
Uniprot IDs
O95983
P31321
PDB IDs
2MB7
6CC8
6CCG
6CEU
6CEV
4DIN
4F9K
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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