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MBD3 and CCNC
Data Source:
BioGRID
(two hybrid)
MBD3
CCNC
Description
methyl-CpG binding domain protein 3
cyclin C
Image
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleoplasm
Cytoplasm
NuRD Complex
Protein-containing Complex
Nucleus
Nucleoplasm
Mediator Complex
Molecular Function
DNA Binding
Protein Binding
Methyl-CpG Binding
Nucleosomal DNA Binding
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Identical Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
DNA Methylation-dependent Heterochromatin Assembly
Brain Development
Heart Development
Aging
Tissue Development
Histone Acetylation
Response To Nutrient Levels
Response To Estradiol
ATP-dependent Chromatin Remodeling
Regulation Of DNA Methylation
Embryonic Organ Development
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
PPARA activates gene expression
NOTCH1 Intracellular Domain Regulates Transcription
Generic Transcription Pathway
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Erectile dysfunction (
30297428
)
Refractive error (
32231278
)
Interacting Genes
76 interacting genes:
AGR2
ANKRD33
ASCL4
ATF7
AURKA
BCL11B
CCDC183
CCHCR1
CCNC
CENPP
CEP70
CEP76
CT55
ERCC6
EXOC4
FAM136A
GADD45GIP1
GATAD2A
GATAD2B
GOLGA2
GOLGA6L9
H3-4
HDAC1
ICA1
IGFBP6
IK
JUN
KDM1A
KDM5B
KRT15
KRT16
LDOC1
LMO3
MAGEA2
MAGEA2B
MBD2
MBD3L1
MBD3L2
MECOM
MEIS3
MEOX1
MEOX2
MIPOL1
MKRN3
MTA2
MTUS2
MYOG
NUTM1
PBX4
PDGFA
PFDN6
PICK1
PKNOX2
PRKAR1B
RAB3IP
RBBP4
RBBP7
RCN3
REL
RINT1
SDCBP
SERTAD3
SMARCA4
SPEN
STMN2
SYCE1
TBC1D19
TET1
TIMM10B
TNNI1
TRIM54
TTC23
USP11
ZBTB7A
ZNF277
ZNF655
80 interacting genes:
ASH2L
BLOC1S2
BTBD2
CCHCR1
CCNH
CDK3
CDK8
CDKN2B
CFAP53
CKS1B
CRX
DYDC1
ERCC3
ESR2
FAM161A
FAM50B
FAM90A1
FOXP2
FOXR2
GADD45GIP1
GLYR1
GOLGA2
GPC4
HSPB1
ISY1
KRT13
KRT15
KRT16
KRT27
KRT31
KRT34
LCN2
LZTS2
MBD3
MBIP
MCM2
MED8
MEOX2
MGST3
MYO15B
NDUFB7
NDUFV2
NEFL
NMNAT1
NRBF2
PAX5
PBXIP1
PLEKHO2
PLIN3
PNMA5
POU6F2
PRPF18
PUF60
RB1
RBM41
REL
RFC5
RIBC1
RPA2
RUSC1
SERTAD3
SHC3
SPAG8
TADA3
TCEANC
TEPSIN
TEX12
TP63
TRAF3IP3
TRIM39
TRIM54
UBE2K
VHL
VTA1
ZFP90
ZNF18
ZNF426
ZNF620
ZNF688
ZNF792
Entrez ID
53615
892
HPRD ID
04653
00456
Ensembl ID
ENSG00000071655
ENSG00000112237
Uniprot IDs
O95983
P24863
Q7Z4L3
PDB IDs
2MB7
6CC8
6CCG
6CEU
6CEV
3RGF
4CRL
4F6S
4F6U
4F6W
4F70
4F7J
4F7L
4F7N
4F7S
4G6L
5BNJ
5CEI
5FGK
5HBE
5HBH
5HBJ
5HNB
5HVY
5I5Z
5ICP
5IDN
5IDP
5XQX
5XS2
6QTG
6QTJ
6R3S
6T41
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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