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MBD3 and RBBP7
Data Source:
HPRD
(in vivo, in vitro)
MBD3
RBBP7
Description
methyl-CpG binding domain protein 3
RB binding protein 7, chromatin remodeling factor
Image
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleoplasm
Cytoplasm
NuRD Complex
Protein-containing Complex
Nucleus
Nucleoplasm
Cytosol
NuRD Complex
ESC/E(Z) Complex
Molecular Function
DNA Binding
Protein Binding
Methyl-CpG Binding
Nucleosomal DNA Binding
RNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
DNA Methylation-dependent Heterochromatin Assembly
Brain Development
Heart Development
Aging
Tissue Development
Histone Acetylation
Response To Nutrient Levels
Response To Estradiol
ATP-dependent Chromatin Remodeling
Regulation Of DNA Methylation
Embryonic Organ Development
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Transcription By RNA Polymerase II
DNA Replication
Negative Regulation Of Cell Growth
CENP-A Containing Nucleosome Assembly
Post-translational Protein Modification
Negative Regulation Of Gene Expression, Epigenetic
Response To Steroid Hormone
Negative Regulation Of G0 To G1 Transition
Cellular Heat Acclimation
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
HDACs deacetylate histones
PKMTs methylate histone lysines
HATs acetylate histones
RMTs methylate histone arginines
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Deposition of new CENPA-containing nucleosomes at the centromere
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Neddylation
Transcriptional Regulation by E2F6
HCMV Early Events
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Interacting Genes
76 interacting genes:
AGR2
ANKRD33
ASCL4
ATF7
AURKA
BCL11B
CCDC183
CCHCR1
CCNC
CENPP
CEP70
CEP76
CT55
ERCC6
EXOC4
FAM136A
GADD45GIP1
GATAD2A
GATAD2B
GOLGA2
GOLGA6L9
H3-4
HDAC1
ICA1
IGFBP6
IK
JUN
KDM1A
KDM5B
KRT15
KRT16
LDOC1
LMO3
MAGEA2
MAGEA2B
MBD2
MBD3L1
MBD3L2
MECOM
MEIS3
MEOX1
MEOX2
MIPOL1
MKRN3
MTA2
MTUS2
MYOG
NUTM1
PBX4
PDGFA
PFDN6
PICK1
PKNOX2
PRKAR1B
RAB3IP
RBBP4
RBBP7
RCN3
REL
RINT1
SDCBP
SERTAD3
SMARCA4
SPEN
STMN2
SYCE1
TBC1D19
TET1
TIMM10B
TNNI1
TRIM54
TTC23
USP11
ZBTB7A
ZNF277
ZNF655
34 interacting genes:
APPL1
APPL2
BCL11A
BCL11B
BRCA1
BRMS1
BRMS1L
BUB3
CREBBP
CYTOR
DHX30
ERCC6
ESR1
FOXK2
H3-4
H3C1
HDAC1
HDAC2
HUWE1
ING1
MBD3
MBD3L2
MTA2
NR2E3
PRKAA2
RB1
RBBP4
RBP1
SALL2
SAP30
SIN3A
SUMO2
SUV39H1
TWIST1
Entrez ID
53615
5931
HPRD ID
04653
04231
Ensembl ID
ENSG00000071655
ENSG00000102054
Uniprot IDs
O95983
Q16576
Q6FHQ0
PDB IDs
2MB7
6CC8
6CCG
6CEU
6CEV
3CFS
3CFV
Enriched GO Terms of Interacting Partners
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