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MBD3 and ICA1
Data Source:
BioGRID
(two hybrid)
MBD3
ICA1
Description
methyl-CpG binding domain protein 3
islet cell autoantigen 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleoplasm
Cytoplasm
NuRD Complex
Protein-containing Complex
Golgi Membrane
Cytoplasm
Golgi Apparatus
Cytosol
Secretory Granule Membrane
Synaptic Vesicle Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
DNA Binding
Protein Binding
Methyl-CpG Binding
Nucleosomal DNA Binding
Protein Binding
Protein Domain Specific Binding
Membrane Curvature Sensor Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
DNA Methylation-dependent Heterochromatin Assembly
Brain Development
Heart Development
Aging
Tissue Development
Histone Acetylation
Response To Nutrient Levels
Response To Estradiol
ATP-dependent Chromatin Remodeling
Regulation Of DNA Methylation
Embryonic Organ Development
Regulation Of Signal Transduction By P53 Class Mediator
Neurotransmitter Transport
Regulation Of Insulin Secretion
Regulation Of Transport
Pathways
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Cognitive function (
24684796
)
Intraocular pressure (
23836780
)
Metabolite levels (Pyroglutamine) (
23934736
)
Night sleep phenotypes (
27126917
)
Obesity-related traits (
23251661
)
Systemic lupus erythematosus (
28714469
)
Interacting Genes
76 interacting genes:
AGR2
ANKRD33
ASCL4
ATF7
AURKA
BCL11B
CCDC183
CCHCR1
CCNC
CENPP
CEP70
CEP76
CT55
ERCC6
EXOC4
FAM136A
GADD45GIP1
GATAD2A
GATAD2B
GOLGA2
GOLGA6L9
H3-4
HDAC1
ICA1
IGFBP6
IK
JUN
KDM1A
KDM5B
KRT15
KRT16
LDOC1
LMO3
MAGEA2
MAGEA2B
MBD2
MBD3L1
MBD3L2
MECOM
MEIS3
MEOX1
MEOX2
MIPOL1
MKRN3
MTA2
MTUS2
MYOG
NUTM1
PBX4
PDGFA
PFDN6
PICK1
PKNOX2
PRKAR1B
RAB3IP
RBBP4
RBBP7
RCN3
REL
RINT1
SDCBP
SERTAD3
SMARCA4
SPEN
STMN2
SYCE1
TBC1D19
TET1
TIMM10B
TNNI1
TRIM54
TTC23
USP11
ZBTB7A
ZNF277
ZNF655
6 interacting genes:
CCDC28A
EXOC5
ING5
MBD3
RAB2A
RAB2B
Entrez ID
53615
3382
HPRD ID
04653
00971
Ensembl ID
ENSG00000071655
ENSG00000003147
Uniprot IDs
O95983
A0A024RA29
Q05084
PDB IDs
2MB7
6CC8
6CCG
6CEU
6CEV
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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