RBBP7 and ING1

Data Source:
HPRD (in vivo)

		RBBP7	ING1
Description		RB binding protein 7, chromatin remodeling factor	inhibitor of growth family member 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol NuRD Complex ESC/E(Z) Complex	Nucleus
	Molecular Function	RNA Binding Protein Binding	Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Post-translational Protein Modification Negative Regulation Of Gene Expression, Epigenetic Response To Steroid Hormone Negative Regulation Of G0 To G1 Transition Cellular Heat Acclimation Regulation Of Signal Transduction By P53 Class Mediator	Cell Cycle Negative Regulation Of Cell Population Proliferation Regulation Of Cell Death Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated
Pathways		PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)
Interacting Genes		34 interacting genes: APPL1 APPL2 BCL11A BCL11B BRCA1 BRMS1 BRMS1L BUB3 CREBBP CYTOR DHX30 ERCC6 ESR1 FOXK2 H3-4 H3C1 HDAC1 HDAC2 HUWE1 ING1 MBD3 MBD3L2 MTA2 NR2E3 PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1	29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		5931	3621
HPRD ID		04231	03337
Ensembl ID		ENSG00000102054	ENSG00000153487
Uniprot IDs		Q16576 Q6FHQ0	A0A0C4DFW2 Q9UK53
PDB IDs		3CFS 3CFV	2QIC
Enriched GO Terms of Interacting Partners?
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