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PJA1 and STAMBP
Data Source:
BioGRID
(enzymatic study)
PJA1
STAMBP
Description
praja ring finger ubiquitin ligase 1
STAM binding protein
Image
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Nucleoplasm
Endosome
Early Endosome
Cytosol
Plasma Membrane
Membrane
Cleavage Furrow
Extracellular Exosome
Molecular Function
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Metallopeptidase Activity
Protein Domain Specific Binding
Metal Ion Binding
Lys63-specific Deubiquitinase Activity
Isopeptidase Activity
Biological Process
Protein Ubiquitination
Protein Catabolic Process
Mitotic Cytokinesis
Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Protein Deubiquitination
Protein Phosphopantetheinylation
Negative Regulation Of Ras Protein Signal Transduction
Protein K63-linked Deubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Metalloprotease DUBs
Drugs
Diseases
GWAS
Birth weight (
31043758
)
Body mass index (
29273807
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Schizophrenia (
25056061
29483656
)
Anti-saccade response (
29064472
)
Blood metabolite levels (
26401656
)
Serum metabolite levels (
23093944
)
Interacting Genes
64 interacting genes:
ABR
ASCC2
ATP5F1C
ATXN3
ATXN3L
CAMK1G
CDK16
COASY
CSAG3
DDX54
EED
ELAC1
ESPL1
EZH2
FGF12
GATD3A
GLO1
GSR
GTF2I
HNRNPC
HNRNPL
HOMER2
JOSD1
KIF22
LCP2
LRG1
MAGEB4
MAGED1
MDM2
METAP2
NAGK
NATD1
NDN
OTUB1
OTUB2
PCCA
PFKFB4
PHGDH
PIP4K2C
RIBC2
SPTBN1
STAC
STAM
STAMBP
SUZ12
TAF9
TK1
TMEM214
TSSK3
TXNDC5
UBE2D2
UBE2D3
UBE2E3
UBE2K
UBE2L3
UBE2U
UCHL3
UCHL5
USP20
USP28
USP5
USP51
USP8
ZNF440
45 interacting genes:
ALAS1
AMN
APOBEC3A
BMPR1B
CASR
CHMP1A
CHMP1B
CHMP2A
CHMP3
CHMP4A
CHMP4B
CHMP4C
CHMP5
CLTC
CTNNBL1
CYP2C9
EPS15
GRAP2
GRB2
IL1RL2
ITGA5
MAP2K5
MAP3K2
NLRP3
NLRP7
NTPCR
PJA1
RECQL5
RNF11
SMAD2
SMAD6
SMAD7
SNCA
SPG7
STAM
STAM2
TNFRSF1A
TP53
TRAF6
TRIP13
UACA
UBC
UBE2S
USP21
USP28
Entrez ID
64219
10617
HPRD ID
02335
05877
Ensembl ID
ENSG00000181191
ENSG00000124356
Uniprot IDs
Q8NG27
A0A140VK54
O95630
PDB IDs
2L0B
2XZE
3RZU
3RZV
5IXF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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