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STAMBP and UBE2S
Data Source:
BioGRID
(enzymatic study)
STAMBP
UBE2S
Description
STAM binding protein
ubiquitin conjugating enzyme E2 S
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Endosome
Early Endosome
Cytosol
Plasma Membrane
Membrane
Cleavage Furrow
Extracellular Exosome
Nucleus
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Metallopeptidase Activity
Protein Domain Specific Binding
Metal Ion Binding
Lys63-specific Deubiquitinase Activity
Isopeptidase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Anaphase-promoting Complex Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Mitotic Cytokinesis
Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Protein Deubiquitination
Protein Phosphopantetheinylation
Negative Regulation Of Ras Protein Signal Transduction
Protein K63-linked Deubiquitination
Protein Polyubiquitination
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Exit From Mitosis
Free Ubiquitin Chain Polymerization
Protein Ubiquitination
Anaphase-promoting Complex-dependent Catabolic Process
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Cell Division
Protein K63-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways
Metalloprotease DUBs
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Anti-saccade response (
29064472
)
Blood metabolite levels (
26401656
)
Serum metabolite levels (
23093944
)
Interacting Genes
45 interacting genes:
ALAS1
AMN
APOBEC3A
BMPR1B
CASR
CHMP1A
CHMP1B
CHMP2A
CHMP3
CHMP4A
CHMP4B
CHMP4C
CHMP5
CLTC
CTNNBL1
CYP2C9
EPS15
GRAP2
GRB2
IL1RL2
ITGA5
MAP2K5
MAP3K2
NLRP3
NLRP7
NTPCR
PJA1
RECQL5
RNF11
SMAD2
SMAD6
SMAD7
SNCA
SPG7
STAM
STAM2
TNFRSF1A
TP53
TRAF6
TRIP13
UACA
UBC
UBE2S
USP21
USP28
42 interacting genes:
AKT1
ANAPC1
ANAPC11
ANAPC2
ANAPC4
ANAPC5
ANAPC7
APP
ATXN3
BIRC2
CCNB1
CDC16
CDC20
CDC23
CDC27
CTNNB1
CYLD
FBXO5
FZR1
GMNN
HERC1
LINC00839
MDM2
OTUB1
OTUD7B
PRKN
PTEN
RBCK1
RNF7
STAMBP
UBA1
UBA6
UBB
UBC
UCHL3
USP15
USP2
USP21
USP5
USP7
VHL
ZRANB1
Entrez ID
10617
27338
HPRD ID
05877
15603
Ensembl ID
ENSG00000124356
ENSG00000108106
Uniprot IDs
A0A140VK54
O95630
Q16763
PDB IDs
2XZE
3RZU
3RZV
5IXF
1ZDN
5BNB
5L9T
6QH3
6QHK
6S96
6S98
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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