STAMBP and AMN

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STAMBP	AMN
Description		STAM binding protein	amnion associated transmembrane protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome	Extracellular Space Plasma Membrane Clathrin-coated Pit Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Endocytic Vesicle Brush Border Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Isopeptidase Activity	Signaling Receptor Binding Protein Binding
	Biological Process	Mitotic Cytokinesis Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination	Receptor-mediated Endocytosis Multicellular Organism Development Excretion Protein Localization Cobalamin Metabolic Process Cobalamin Transport High-density Lipoprotein Particle Clearance Golgi To Plasma Membrane Protein Transport
Pathways		Metalloprotease DUBs	Cobalamin (Cbl, vitamin B12) transport and metabolism Defective AMN causes hereditary megaloblastic anemia 1 Defective CUBN causes hereditary megaloblastic anemia 1 HDL clearance
Drugs			Hydroxocobalamin
Diseases
GWAS		Anti-saccade response ( 29064472) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944)	Body mass index ( 26426971)
Interacting Genes		45 interacting genes: ALAS1 AMN APOBEC3A BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP3 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28	1 interacting genes: STAMBP
Entrez ID		10617	81693
HPRD ID		05877	09314
Ensembl ID		ENSG00000124356	ENSG00000166126
Uniprot IDs		A0A140VK54 O95630	B3KP64 Q9BXJ7
PDB IDs		2XZE 3RZU 3RZV 5IXF	6GJE
Enriched GO Terms of Interacting Partners?
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