PJA1 and KIF22

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PJA1	KIF22
Description		praja ring finger ubiquitin ligase 1	kinesin family member 22
Image
GO Annotations	Cellular Component	Cytoplasm	Kinetochore Chromatin Nucleus Cytosol Kinesin Complex Microtubule Nuclear Speck Mitotic Spindle
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Mitotic Cell Cycle DNA Repair Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Sister Chromatid Cohesion Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Metaphase Plate Congression
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)	Red blood cell traits ( 23222517)
Interacting Genes		64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440	6 interacting genes: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL
Entrez ID		64219	3835
HPRD ID		02335	04445
Ensembl ID		ENSG00000181191	ENSG00000079616
Uniprot IDs		Q8NG27	A0A024R632 B7Z9T5 Q14807
PDB IDs		2L0B	2EDU 6NJE
Enriched GO Terms of Interacting Partners?
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