PJA1 and STAC

  • Data Source:
  • BioGRID (enzymatic study)

PJA1

STAC

Description praja ring finger ubiquitin ligase 1 SH3 and cysteine rich domain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325)
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701)
  • Asthma ( 29273806)
  • Brooding (response to stress) ( 30886212)
  • Celiac disease ( 23936387)
  • Erectile dysfunction in type 1 diabetes ( 22704111)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649)
  • Metabolite levels ( 23823483)
  • Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)
Interacting Genes 64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440 22 interacting genes: APP FBXO25 GOLGA2 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 MEOX2 NBPF19 NCKIPSD NEDD4L NOTCH2NLA PAX5 PAX6 PJA1 POU6F2 RNF208 STAT5B TRIP6 TRMO
Entrez ID 64219 6769
HPRD ID 02335 11890
Ensembl ID ENSG00000181191 ENSG00000144681
Uniprot IDs Q8NG27 B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469
PDB IDs 2L0B 2DL4 6B25
Enriched GO Terms of Interacting Partners?
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