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MAGEA2 and MBD3
Data Source:
BioGRID
(two hybrid)
MAGEA2
MBD3
Description
MAGE family member A2
methyl-CpG binding domain protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
PML Body
Chromatin
Heterochromatin
Nucleoplasm
Cytoplasm
NuRD Complex
Protein-containing Complex
Molecular Function
Protein Binding
Ubiquitin Protein Ligase Binding
Histone Deacetylase Binding
Repressing Transcription Factor Binding
DNA Binding
Protein Binding
Methyl-CpG Binding
Nucleosomal DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Protein Sumoylation
Cellular Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Signal Transduction By P53 Class Mediator
Cellular Senescence
Negative Regulation Of Protein Acetylation
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
DNA Methylation-dependent Heterochromatin Assembly
Brain Development
Heart Development
Aging
Tissue Development
Histone Acetylation
Response To Nutrient Levels
Response To Estradiol
ATP-dependent Chromatin Remodeling
Regulation Of DNA Methylation
Embryonic Organ Development
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Interacting Genes
21 interacting genes:
ACSM1
ANKRD45
BEX1
BEX2
CCDC185
CEP57
COQ4
COX7C
DYNLRB1
MBD3
MDM2
NTAQ1
P4HA3
PHKG2
POLL
PSMC1
SEPTIN5
SMARCD1
TNIP3
TP53
TRIM28
76 interacting genes:
AGR2
ANKRD33
ASCL4
ATF7
AURKA
BCL11B
CCDC183
CCHCR1
CCNC
CENPP
CEP70
CEP76
CT55
ERCC6
EXOC4
FAM136A
GADD45GIP1
GATAD2A
GATAD2B
GOLGA2
GOLGA6L9
H3-4
HDAC1
ICA1
IGFBP6
IK
JUN
KDM1A
KDM5B
KRT15
KRT16
LDOC1
LMO3
MAGEA2
MAGEA2B
MBD2
MBD3L1
MBD3L2
MECOM
MEIS3
MEOX1
MEOX2
MIPOL1
MKRN3
MTA2
MTUS2
MYOG
NUTM1
PBX4
PDGFA
PFDN6
PICK1
PKNOX2
PRKAR1B
RAB3IP
RBBP4
RBBP7
RCN3
REL
RINT1
SDCBP
SERTAD3
SMARCA4
SPEN
STMN2
SYCE1
TBC1D19
TET1
TIMM10B
TNNI1
TRIM54
TTC23
USP11
ZBTB7A
ZNF277
ZNF655
Entrez ID
4101
53615
HPRD ID
02165
04653
Ensembl ID
ENSG00000268606
ENSG00000071655
Uniprot IDs
A0A024RC17
P43356
Q6P448
O95983
PDB IDs
2MB7
6CC8
6CCG
6CEU
6CEV
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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