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MAGEA2 and CEP57
Data Source:
BioGRID
(two hybrid)
MAGEA2
CEP57
Description
MAGE family member A2
centrosomal protein 57
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
PML Body
Nucleus
Golgi Apparatus
Centrosome
Cytosol
Microtubule
Molecular Function
Protein Binding
Ubiquitin Protein Ligase Binding
Histone Deacetylase Binding
Repressing Transcription Factor Binding
Protein Binding
Microtubule Binding
Fibroblast Growth Factor Binding
Protein Homodimerization Activity
Gamma-tubulin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Protein Sumoylation
Cellular Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Signal Transduction By P53 Class Mediator
Cellular Senescence
Negative Regulation Of Protein Acetylation
G2/M Transition Of Mitotic Cell Cycle
Spermatid Development
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Anchoring
Protein Homooligomerization
Ciliary Basal Body-plasma Membrane Docking
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Cognitive ability (MTAG) (
29186694
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Feeling worry (
29500382
)
Intelligence (MTAG) (
29326435
)
Rheumatoid arthritis (
30423114
24390342
)
Triglyceride levels x loop diuretics use interaction (
31806883
)
Interacting Genes
21 interacting genes:
ACSM1
ANKRD45
BEX1
BEX2
CCDC185
CEP57
COQ4
COX7C
DYNLRB1
MBD3
MDM2
NTAQ1
P4HA3
PHKG2
POLL
PSMC1
SEPTIN5
SMARCD1
TNIP3
TP53
TRIM28
47 interacting genes:
AARD
ABI2
APP
ATPAF2
CCDC136
CCDC138
CCDC185
CCHCR1
CEP63
DEUP1
DISC1
FBXL3
FGF2
GCC1
HSF2BP
KDM1A
KLC4
KRT13
KRT15
KRT31
KRT4
KRT40
KRT75
KRT8
KRT83
KRT86
LMO3
MAGEA2
MAGEA2B
MEGF10
MIA2
MYC
OIP5
PKN1
PPP1R13B
RABEP1
RALBP1
RASSF10
SH3BP5L
SPDEF
TEX12
TFIP11
TSGA10
TSPYL4
TXLNA
TXLNB
UIMC1
Entrez ID
4101
9702
HPRD ID
02165
16261
Ensembl ID
ENSG00000268606
ENSG00000166037
Uniprot IDs
A0A024RC17
P43356
Q6P448
Q86XR8
PDB IDs
4L0R
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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