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NINL and KRT1
Data Source:
BioGRID
(two hybrid)
NINL
KRT1
Description
ninein like
keratin 1
Image
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Microtubule
Microtubule Cytoskeleton
Intercellular Bridge
Cornified Envelope
Extracellular Region
Extracellular Space
Nucleus
Cytosol
Cytoskeleton
Membrane
Keratin Filament
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Molecular Function
Calcium Ion Binding
Protein Binding
Protein Binding
Carbohydrate Binding
Structural Constituent Of Skin Epidermis
Signaling Receptor Activity
Protein Heterodimerization Activity
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Anchoring At Centrosome
Ciliary Basal Body-plasma Membrane Docking
Complement Activation, Lectin Pathway
Retina Homeostasis
Response To Oxidative Stress
Peptide Cross-linking
Keratinization
Fibrinolysis
Neutrophil Degranulation
Regulation Of Angiogenesis
Negative Regulation Of Inflammatory Response
Protein Heterotetramerization
Establishment Of Skin Barrier
Cornification
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Drugs
Zinc
Copper
Zinc acetate
Diseases
Epidermolytic palmoplantar keratoderma (EPPK)
Ichthyosis hystrix, Curth-Macklin type
Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
Striate palmoplantar keratoderma
GWAS
Brain morphology (MOSTest) (
32665545
)
Macular thickness (
30535121
)
Telomere length (
30185882
)
Urate levels (
31578528
)
Interacting Genes
51 interacting genes:
AKAP17A
APEX2
AURKB
CBY2
CCDC130
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
ELOA
ERBB2
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
KRT1
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
PRPF18
PRPF3
RBM41
RCOR3
RGS2
RIBC2
RNF40
SH2D4A
SH3BP5L
SYT17
TCEANC
TNNT1
TSPYL4
UTP14A
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
51 interacting genes:
AMOTL2
CALB2
CSTA
DSP
EVPL
F12
FANCA
FANCC
FFAR2
GOLGA2
GOLGA6L9
HAUS1
HMG20A
HOOK2
IVL
KNG1
KRT13
KRT14
KRT15
KRT16
KRT19
KRT24
KRT25
KRT26
KRT27
KRT28
KRT31
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT39
KRT5
LINC00839
LORICRIN
MBL2
NINL
NUP62
PI3
PRKCE
RINT1
SGTB
TFIP11
TLCD4
TRIM54
U2AF1
U2AF1L5
UBE3A
YWHAQ
Entrez ID
22981
3848
HPRD ID
11120
00763
Ensembl ID
ENSG00000101004
ENSG00000167768
Uniprot IDs
Q9Y2I6
P04264
PDB IDs
4ZRY
6E2J
6UUI
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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