KRT1 and KRT24

Data Source:
BioGRID (two hybrid)

		KRT1	KRT24
Description		keratin 1	keratin 24
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Membrane Keratin Filament Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding Structural Constituent Of Skin Epidermis Signaling Receptor Activity Protein Heterodimerization Activity	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Peptide Cross-linking Keratinization Fibrinolysis Neutrophil Degranulation Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Protein Heterotetramerization Establishment Of Skin Barrier Cornification	Biological_process Keratinization Cornification
Pathways		Neutrophil degranulation Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Copper Zinc acetate
Diseases		Epidermolytic palmoplantar keratoderma (EPPK) Ichthyosis hystrix, Curth-Macklin type Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE) Striate palmoplantar keratoderma
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		51 interacting genes: AMOTL2 CALB2 CSTA DSP EVPL F12 FANCA FANCC FFAR2 GOLGA2 GOLGA6L9 HAUS1 HMG20A HOOK2 IVL KNG1 KRT13 KRT14 KRT15 KRT16 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT5 LINC00839 LORICRIN MBL2 NINL NUP62 PI3 PRKCE RINT1 SGTB TFIP11 TLCD4 TRIM54 U2AF1 U2AF1L5 UBE3A YWHAQ	32 interacting genes: AARD ABI2 ABI3 AMOT BFSP2 C1orf109 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT20 KRT3 KRT4 KRT5 KRT6C KRT71 KRT72 KRT75 KRT79 KRT8 KRT80 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA
Entrez ID		3848	192666
HPRD ID		00763	09668
Ensembl ID		ENSG00000167768	ENSG00000167916
Uniprot IDs		P04264	Q2M2I5
PDB IDs		4ZRY 6E2J 6UUI
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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