NINL and DCTN5

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		NINL	DCTN5
Description		ninein like	dynactin subunit 5
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Microtubule Microtubule Cytoskeleton Intercellular Bridge	Condensed Chromosome Kinetochore Nucleoplasm Centrosome Cytosol Nuclear Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking	Ventricular Septum Development Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Aorta Development Coronary Vasculature Development
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)	Bipolar disorder ( 17554300)
Interacting Genes		51 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	5 interacting genes: DYNLL1 FATE1 NINL PMEPA1 RBPMS
Entrez ID		22981	84516
HPRD ID		11120	14551
Ensembl ID		ENSG00000101004	ENSG00000166847
Uniprot IDs		Q9Y2I6	Q9BTE1
PDB IDs			5NW4
Enriched GO Terms of Interacting Partners?
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