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KRT1 and KRT28
Data Source:
BioGRID
(two hybrid)
KRT1
KRT28
Description
keratin 1
keratin 28
Image
No pdb structure
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Extracellular Space
Nucleus
Cytosol
Cytoskeleton
Membrane
Keratin Filament
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Cytosol
Intermediate Filament
Extracellular Exosome
Molecular Function
Protein Binding
Carbohydrate Binding
Structural Constituent Of Skin Epidermis
Signaling Receptor Activity
Protein Heterodimerization Activity
Molecular_function
Structural Molecule Activity
Protein Binding
Biological Process
Complement Activation, Lectin Pathway
Retina Homeostasis
Response To Oxidative Stress
Peptide Cross-linking
Keratinization
Fibrinolysis
Neutrophil Degranulation
Regulation Of Angiogenesis
Negative Regulation Of Inflammatory Response
Protein Heterotetramerization
Establishment Of Skin Barrier
Cornification
Biological_process
Keratinization
Cornification
Pathways
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Keratinization
Formation of the cornified envelope
Drugs
Zinc
Copper
Zinc acetate
Diseases
Epidermolytic palmoplantar keratoderma (EPPK)
Ichthyosis hystrix, Curth-Macklin type
Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
Striate palmoplantar keratoderma
GWAS
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Glucose homeostasis traits (
25524916
)
Interacting Genes
51 interacting genes:
AMOTL2
CALB2
CSTA
DSP
EVPL
F12
FANCA
FANCC
FFAR2
GOLGA2
GOLGA6L9
HAUS1
HMG20A
HOOK2
IVL
KNG1
KRT13
KRT14
KRT15
KRT16
KRT19
KRT24
KRT25
KRT26
KRT27
KRT28
KRT31
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT39
KRT5
LINC00839
LORICRIN
MBL2
NINL
NUP62
PI3
PRKCE
RINT1
SGTB
TFIP11
TLCD4
TRIM54
U2AF1
U2AF1L5
UBE3A
YWHAQ
19 interacting genes:
ABI3
CCDC196
DEUP1
KRT1
KRT3
KRT4
KRT5
KRT6A
KRT6B
KRT71
KRT79
KRT8
KRT80
KRT81
KRT86
NUP58
UCHL5
USHBP1
WASHC1
Entrez ID
3848
162605
HPRD ID
00763
17245
Ensembl ID
ENSG00000167768
ENSG00000173908
Uniprot IDs
P04264
Q7Z3Y7
PDB IDs
4ZRY
6E2J
6UUI
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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