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NINL and CCDC146
Data Source:
BioGRID
(two hybrid)
NINL
CCDC146
Description
ninein like
coiled-coil domain containing 146
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Microtubule
Microtubule Cytoskeleton
Intercellular Bridge
Cytoplasm
Centriole
Cytoskeleton
Molecular Function
Calcium Ion Binding
Protein Binding
Protein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Anchoring At Centrosome
Ciliary Basal Body-plasma Membrane Docking
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Macular thickness (
30535121
)
Telomere length (
30185882
)
Urate levels (
31578528
)
Body mass index (
28892062
)
Response to amphetamines (
22952603
)
Interacting Genes
51 interacting genes:
AKAP17A
APEX2
AURKB
CBY2
CCDC130
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
ELOA
ERBB2
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
KRT1
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
PRPF18
PRPF3
RBM41
RCOR3
RGS2
RIBC2
RNF40
SH2D4A
SH3BP5L
SYT17
TCEANC
TNNT1
TSPYL4
UTP14A
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
71 interacting genes:
AKAP9
BLOC1S2
CBY2
CCDC136
CCDC197
CCNDBP1
CDR2
CDR2L
CENPH
CEP170P1
CEP44
DTNBP1
FSD2
GAS8
GMNN
GOLGA2
GOLGA6L9
GPRASP2
GRAMD4
HSF2BP
INSYN1
KIFC3
KRT16
KRT18
KRT19
KRT24
KRT26
KRT27
KRT31
KRT34
KRT38
KRT40
KRT86
LHX3
MAGEA11
MAGEA6
MCC
MED4
MIPOL1
MRFAP1
MTUS2
N4BP3
NAP1L2
NECAB2
NINL
NUP62
PDE4DIP
PLEKHF2
PNMA1
PPP2R3C
PROSER3
PSMC6
RINT1
RNF40
RPGRIP1
SH3BP1
SYCE1L
TEPSIN
TFIP11
THOC7
TNR
TPM3
TRAF1
TRIM23
TRIM54
TRIML2
TSC22D4
TXLNA
USHBP1
VPS28
VPS52
Entrez ID
22981
57639
HPRD ID
11120
11150
Ensembl ID
ENSG00000101004
ENSG00000135205
Uniprot IDs
Q9Y2I6
Q8IYE0
Q96MS1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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