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KRT1 and AMOTL2
Data Source:
BioGRID
(two hybrid)
KRT1
AMOTL2
Description
keratin 1
angiomotin like 2
Image
No pdb structure
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Extracellular Space
Nucleus
Cytosol
Cytoskeleton
Membrane
Keratin Filament
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Cytosol
Plasma Membrane
Bicellular Tight Junction
Cytoplasmic Vesicle
Recycling Endosome
Molecular Function
Protein Binding
Carbohydrate Binding
Structural Constituent Of Skin Epidermis
Signaling Receptor Activity
Protein Heterodimerization Activity
Protein Binding
Biological Process
Complement Activation, Lectin Pathway
Retina Homeostasis
Response To Oxidative Stress
Peptide Cross-linking
Keratinization
Fibrinolysis
Neutrophil Degranulation
Regulation Of Angiogenesis
Negative Regulation Of Inflammatory Response
Protein Heterotetramerization
Establishment Of Skin Barrier
Cornification
Angiogenesis
Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
Wnt Signaling Pathway
Actin Cytoskeleton Organization
Regulation Of Cell Migration
Hippo Signaling
Pathways
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Signaling by Hippo
Drugs
Zinc
Copper
Zinc acetate
Diseases
Epidermolytic palmoplantar keratoderma (EPPK)
Ichthyosis hystrix, Curth-Macklin type
Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
Striate palmoplantar keratoderma
GWAS
Cadmium levels (
26025379
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Interacting Genes
51 interacting genes:
AMOTL2
CALB2
CSTA
DSP
EVPL
F12
FANCA
FANCC
FFAR2
GOLGA2
GOLGA6L9
HAUS1
HMG20A
HOOK2
IVL
KNG1
KRT13
KRT14
KRT15
KRT16
KRT19
KRT24
KRT25
KRT26
KRT27
KRT28
KRT31
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT39
KRT5
LINC00839
LORICRIN
MBL2
NINL
NUP62
PI3
PRKCE
RINT1
SGTB
TFIP11
TLCD4
TRIM54
U2AF1
U2AF1L5
UBE3A
YWHAQ
91 interacting genes:
AMOT
BFSP2
BLZF1
BRMS1L
BYSL
CARD9
CCDC185
CCDC196
CCDC57
CCHCR1
CDC37
CDR2
CHCHD3
CINP
CYTH4
DAXX
DDIT3
DTNB
DYNLL1
DZIP1L
EIF4E2
FAM184A
FAM90A1
FBXO7
FCRL5
FXR2
GCC1
GNG11
GNG5
GOLGA2
GSTM5
KIF9
KRT1
KRT13
KRT15
KRT19
KRT20
KRT31
KRT38
KRTAP10-5
KRTAP4-2
L3MBTL2
LMNB2
LMO3
LMO4
MAD1L1
MAGEA4
MAGOHB
MFAP1
MORF4L2
MPP1
MTMR6
MTNR1A
MYO5B
NDC80
NF2
NFIL3
NME7
NTAQ1
PIBF1
PPP2CA
PPP2R1A
PRKAA2
PRPF18
PSMC3
RAD51D
RALBP1
RASAL3
RASSF5
RNF20
RNF40
RNF8
SAAL1
SH3RF2
SMARCE1
SOGA1
SP100
SPAG5
SPOP
SPP1
TCEA2
THRA
TMCC2
TNKS2
TRAF2
TRIM27
TSGA10IP
YES1
ZBED1
ZBTB16
ZGPAT
Entrez ID
3848
51421
HPRD ID
00763
16485
Ensembl ID
ENSG00000167768
ENSG00000114019
Uniprot IDs
P04264
Q9Y2J4
PDB IDs
4ZRY
6E2J
6UUI
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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