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NINL and LRSAM1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NINL
LRSAM1
Description
ninein like
leucine rich repeat and sterile alpha motif containing 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Microtubule
Microtubule Cytoskeleton
Intercellular Bridge
Cytoplasm
Cytosol
Membrane
Molecular Function
Calcium Ion Binding
Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Anchoring At Centrosome
Ciliary Basal Body-plasma Membrane Docking
Protein Polyubiquitination
Autophagy
Protein Catabolic Process
Negative Regulation Of Endocytosis
Viral Budding
Protein Autoubiquitination
Ubiquitin-dependent Endocytosis
Positive Regulation Of Xenophagy
Positive Regulation Of Autophagosome Assembly
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Macular thickness (
30535121
)
Telomere length (
30185882
)
Urate levels (
31578528
)
Mean corpuscular volume (
32888494
)
Interacting Genes
51 interacting genes:
AKAP17A
APEX2
AURKB
CBY2
CCDC130
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
ELOA
ERBB2
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
KRT1
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
PRPF18
PRPF3
RBM41
RCOR3
RGS2
RIBC2
RNF40
SH2D4A
SH3BP5L
SYT17
TCEANC
TNNT1
TSPYL4
UTP14A
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
42 interacting genes:
ATXN1
ATXN7
CCDC6
DMAP1
FAM178B
GABARAPL2
GPR108
GRIK5
GSK3A
KLC1
MAGEA1
MDM4
MGAT4B
MKRN3
MUTYH
MYL2
NINL
PHF23
RNF111
RXRG
TERF1
TNFRSF10C
TRIM17
TRIM74
TSG101
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2H
UBE2I
UBE2J1
UBE2K
UBE2N
UBE2W
UEVLD
USP2
USP21
VPS11
XAF1
ZMAT4
Entrez ID
22981
90678
HPRD ID
11120
14325
Ensembl ID
ENSG00000101004
ENSG00000148356
Uniprot IDs
Q9Y2I6
A0A024R870
Q6UWE0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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