NINL and ZNF426

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NINL	ZNF426
Description		ninein like	zinc finger protein 426
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Microtubule Microtubule Cytoskeleton Intercellular Bridge	Nucleus
	Molecular Function	Calcium Ion Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking	Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Generic Transcription Pathway
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		51 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646	45 interacting genes: ACTN3 ANKRD11 ARMC7 ATPAF2 BYSL CALCOCO2 CARD9 CCDC85B CCNC CDK18 CEP70 CIB3 CTNNA3 DUSP4 EFEMP2 ENKD1 FAM161A GLRX3 GSDMD HEXIM2 KCTD9 KRT3 KRTAP4-12 LNX1 LONRF1 LPXN LZTS2 MAGOHB MALSU1 MAP2K5 MDFI MPPE1 MTUS2 NATD1 NINL OPTN PARVG RFC5 RHOJ TEKT4 TSGA10 USP25 ZGPAT ZNF330 ZSCAN23
Entrez ID		22981	79088
HPRD ID		11120	15787
Ensembl ID		ENSG00000101004	ENSG00000130818
Uniprot IDs		Q9Y2I6	A0A024R7D7 K7EME3 K7ER43 Q59EH4 Q9BUY5
PDB IDs
Enriched GO Terms of Interacting Partners?
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