SUV39H2 and WIZ

Data Source:
BioGRID (two hybrid)

		SUV39H2	WIZ
Description		suppressor of variegation 3-9 homolog 2	WIZ zinc finger
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm Midbody Extracellular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Corepressor Binding Protein Binding Protein-containing Complex Binding Metal Ion Binding Histone Methyltransferase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte percentage of white cells ( 32888494)
Interacting Genes		41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	16 interacting genes: C8orf33 CDKN1A CRBN DOK5 EHMT1 EHMT2 OSGEP PIN1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1
Entrez ID		79723	58525
HPRD ID		07580	11686
Ensembl ID		ENSG00000152455	ENSG00000011451
Uniprot IDs		Q9H5I1	A0A2R8YFV2 M0QXA7 O95785
PDB IDs		2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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