SUV39H2 and CBX7

Data Source:
BioGRID (protein complementation assay)

		SUV39H2	CBX7
Description		suppressor of variegation 3-9 homolog 2	chromobox 7
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytosol PcG Protein Complex PRC1 Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Lymphocyte counts ( 32888494 27863252) Menarche (age at onset) ( 25231870) Monocyte count ( 32888494) Multiple myeloma ( 26007630 23955597) Multiple myeloma and monoclonal gammopathy ( 26007630) Neutrophil count ( 32888494) White blood cell count ( 32888494 27863252)
Interacting Genes		41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	8 interacting genes: B3GNT5 H3-4 PCGF1 PCGF5 PCGF6 RING1 SUV39H2 ZRANB1
Entrez ID		79723	23492
HPRD ID		07580	12234
Ensembl ID		ENSG00000152455	ENSG00000100307
Uniprot IDs		Q9H5I1	A0A024R1Q2 B0QYP2 O95931 Q4PNR6
PDB IDs		2R3A 6P0R	2K1B 2L12 2L1B 3GS2 4MN3 5EPJ 6V2R
Enriched GO Terms of Interacting Partners?
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