WIZ and SUV39H2

Data Source:
BioGRID (two hybrid)

		WIZ	SUV39H2
Description		WIZ zinc finger	suppressor of variegation 3-9 homolog 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody Extracellular Exosome	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Corepressor Binding Protein Binding Protein-containing Complex Binding Metal Ion Binding Histone Methyltransferase Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte percentage of white cells ( 32888494)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		16 interacting genes: C8orf33 CDKN1A CRBN DOK5 EHMT1 EHMT2 OSGEP PIN1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1	41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		58525	79723
HPRD ID		11686	07580
Ensembl ID		ENSG00000011451	ENSG00000152455
Uniprot IDs		A0A2R8YFV2 M0QXA7 O95785	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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