SUV39H2 and MCM3AP

Data Source:
BioGRID (two hybrid)

		SUV39H2	MCM3AP
Description		suppressor of variegation 3-9 homolog 2	minichromosome maintenance complex component 3 associated protein
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Nuclear Membrane Nuclear Pore Nuclear Basket Transcription Export Complex 2
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	Nucleic Acid Binding Chromatin Binding Histone Acetyltransferase Activity Protein Binding H3 Histone Acetyltransferase Activity Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	MRNA Export From Nucleus Somatic Hypermutation Of Immunoglobulin Genes Poly(A)+ MRNA Export From Nucleus Nucleosome Organization Histone H3 Acetylation
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Monocyte percentage of white cells ( 32888494) Periodontitis ( 30218097) Testicular germ cell tumor ( 25877299 28604728 23666240)
Interacting Genes		41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	19 interacting genes: APC CDC25A CDC42 CDC73 CLSTN1 CRMP1 ENY2 EP300 FAM118B MCM3 NUDT5 POLR2G RAC1 SMAD3 SMAD9 SUV39H2 TAF1D TMEM216 TSC22D1
Entrez ID		79723	8888
HPRD ID		07580	04483
Ensembl ID		ENSG00000152455	ENSG00000160294
Uniprot IDs		Q9H5I1	O60318
PDB IDs		2R3A 6P0R	4DHX
Enriched GO Terms of Interacting Partners?
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