WIZ and RPS10

Data Source:
BioGRID (two hybrid)

		WIZ	RPS10
Description		WIZ zinc finger	ribosomal protein S10
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody Extracellular Exosome	Nucleoplasm Nucleolus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Corepressor Binding Protein Binding Protein-containing Complex Binding Metal Ion Binding Histone Methyltransferase Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases			Diamond-Blackfan anemia (DBA)
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte percentage of white cells ( 32888494)	Adult body size ( 32376654) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Estimated glomerular filtration rate ( 31015462 30604766) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		16 interacting genes: C8orf33 CDKN1A CRBN DOK5 EHMT1 EHMT2 OSGEP PIN1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1	16 interacting genes: APP DMPK DNMT3B DUX4 DVL3 EED FBXO25 HAP1 HIP1 KAT7 PFN2 PTTG1 SYK TCF25 WIZ XRCC6
Entrez ID		58525	6204
HPRD ID		11686	04697
Ensembl ID		ENSG00000011451	ENSG00000124614
Uniprot IDs		A0A2R8YFV2 M0QXA7 O95785	P46783
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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