SUV39H2 and POLR3F

Data Source:
BioGRID (two hybrid)

		SUV39H2	POLR3F
Description		suppressor of variegation 3-9 homolog 2	RNA polymerase III subunit F
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	Double-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		PKMTs methylate histone lysines	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Refractive error ( 32231278)
Interacting Genes		41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRPF4B RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89
Entrez ID		79723	10621
HPRD ID		07580	15156
Ensembl ID		ENSG00000152455	ENSG00000132664
Uniprot IDs		Q9H5I1	Q05DB8 Q9H1D9
PDB IDs		2R3A 6P0R	2DK5 2YU3
Enriched GO Terms of Interacting Partners?
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