SUV39H2 and MTF2

Data Source:
BioGRID (two hybrid)

		SUV39H2	MTF2
Description		suppressor of variegation 3-9 homolog 2	metal response element binding transcription factor 2
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Focal Adhesion ESC/E(Z) Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Corepressor Binding DNA Binding Chromatin Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Segment Specification Stem Cell Population Maintenance Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation Cellular Response To Leukemia Inhibitory Factor
Pathways		PKMTs methylate histone lysines	PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Plasma clusterin levels ( 26545630) Response to lurasidone in schizophrenia ( 29730043) Triglyceride levels ( 32154731)
Interacting Genes		41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	12 interacting genes: CDKN2D CREB1 GPRASP1 GSK3B KDM1A PIK3R3 PRKD2 PRMT6 SMAD3 SUV39H1 SUV39H2 TMED9
Entrez ID		79723	22823
HPRD ID		07580	14342
Ensembl ID		ENSG00000152455	ENSG00000143033
Uniprot IDs		Q9H5I1	B4DZ69 B4DZG1 Q7Z534 Q9Y483
PDB IDs		2R3A 6P0R	5XFR
Enriched GO Terms of Interacting Partners?
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