Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
STXBP1 and CENPP
Data Source:
BioGRID
(two hybrid)
STXBP1
CENPP
Description
syntaxin binding protein 1
centromere protein P
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoskeleton
Plasma Membrane
Secretory Granule
Axon
Platelet Alpha Granule
Protein-containing Complex
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Molecular Function
SNARE Binding
RNA Binding
Protein Binding
Syntaxin-1 Binding
Protein Kinase Binding
Protein Domain Specific Binding
Syntaxin Binding
Identical Protein Binding
Phospholipase Binding
Protein N-terminus Binding
Protein Binding
Biological Process
Platelet Degranulation
Developmental Process Involved In Reproduction
Intracellular Protein Transport
Vesicle Docking Involved In Exocytosis
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Axon Target Recognition
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Priming
Synaptic Vesicle Maturation
Vesicle-mediated Transport
Negative Regulation Of Protein-containing Complex Assembly
Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Negative Regulation Of Synaptic Transmission, GABAergic
Response To Estradiol
SNARE Complex Assembly
Regulation Of SNARE Complex Assembly
Positive Regulation Of Mast Cell Degranulation
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Calcium Ion-dependent Exocytosis
Protein Stabilization
Long-term Synaptic Depression
Platelet Aggregation
Cellular Response To Interferon-gamma
Protein Localization To Plasma Membrane
Presynaptic Dense Core Vesicle Exocytosis
Positive Regulation Of Vesicle Docking
Positive Regulation Of Glutamate Secretion, Neurotransmission
Regulation Of Acrosomal Vesicle Exocytosis
CENP-A Containing Nucleosome Assembly
Pathways
Regulation of insulin secretion
Neurexins and neuroligins
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS
Body size at age 10 (
32376654
)
Whole brain grey matter density (
31530798
)
Blood protein levels (
29875488
)
End-stage renal disease (
29885931
)
HDL cholesterol levels (
32203549
)
Height (
28552196
31562340
)
Malaria (
31844061
)
Pulse pressure (
30578418
)
Systolic blood pressure (
30224653
30578418
)
Triglyceride levels (
32203549
)
Urate levels (
31578528
)
Interacting Genes
34 interacting genes:
APBA1
APBA2
APP
BRME1
CDK5
CDK5R1
CENPP
DOC2A
DOC2B
HGS
MAPK1
MAPT
MEOX2
MTDH
MTNR1A
NEFH
NEFM
PLD1
PLD2
PRKCA
PRKCB
PRKCG
SPICE1
SPTBN1
SQSTM1
STX19
STX1A
STX1B
STX2
STX3
STX5
SYTL4
TRIM38
USO1
27 interacting genes:
ATP6V0D2
BACH2
C2orf88
CCDC33
CCDC85B
CENPO
CEP44
GOLGA2
HAUS1
KIAA1328
KLC3
LMNA
MBD3
NHLH1
NTAQ1
PKNOX2
POLR3K
RNF126
RPIA
SERTAD3
STXBP1
SYCE1L
TEX11
TOX2
USHBP1
ZNF341
ZNF765
Entrez ID
6812
401541
HPRD ID
04235
17989
Ensembl ID
ENSG00000136854
ENSG00000188312
Uniprot IDs
P61764
Q6IPU0
Q7Z672
PDB IDs
6L03
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?