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CENPP and POLR3K
Data Source:
BioGRID
(two hybrid)
CENPP
POLR3K
Description
centromere protein P
RNA polymerase III subunit K
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Nucleoplasm
RNA Polymerase III Complex
Nucleolus
Cytosol
Molecular Function
Protein Binding
Nucleic Acid Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Zinc Ion Binding
Biological Process
CENP-A Containing Nucleosome Assembly
Transcription By RNA Polymerase III
Termination Of RNA Polymerase III Transcription
Positive Regulation Of Type I Interferon Production
TRNA 3'-trailer Cleavage
Innate Immune Response
Defense Response To Virus
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
End-stage renal disease (
29885931
)
HDL cholesterol levels (
32203549
)
Height (
28552196
31562340
)
Malaria (
31844061
)
Pulse pressure (
30578418
)
Systolic blood pressure (
30224653
30578418
)
Triglyceride levels (
32203549
)
Urate levels (
31578528
)
Body mass index (
26426971
)
Mean corpuscular volume (
32888494
)
Red blood cell traits (
23446634
)
Interacting Genes
27 interacting genes:
ATP6V0D2
BACH2
C2orf88
CCDC33
CCDC85B
CENPO
CEP44
GOLGA2
HAUS1
KIAA1328
KLC3
LMNA
MBD3
NHLH1
NTAQ1
PKNOX2
POLR3K
RNF126
RPIA
SERTAD3
STXBP1
SYCE1L
TEX11
TOX2
USHBP1
ZNF341
ZNF765
3 interacting genes:
CENPP
SDCBP
TRIM69
Entrez ID
401541
51728
HPRD ID
17989
16187
Ensembl ID
ENSG00000188312
ENSG00000161980
Uniprot IDs
Q6IPU0
Q7Z672
Q9Y2Y1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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