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STXBP1 and SYTL4
Data Source:
BioGRID
(two hybrid)
HPRD
(in vitro, in vivo)
STXBP1
SYTL4
Description
syntaxin binding protein 1
synaptotagmin like 4
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoskeleton
Plasma Membrane
Secretory Granule
Axon
Platelet Alpha Granule
Protein-containing Complex
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Endosome
Plasma Membrane
Extrinsic Component Of Membrane
Transport Vesicle Membrane
Platelet Alpha Granule Membrane
Exocytic Vesicle
Molecular Function
SNARE Binding
RNA Binding
Protein Binding
Syntaxin-1 Binding
Protein Kinase Binding
Protein Domain Specific Binding
Syntaxin Binding
Identical Protein Binding
Phospholipase Binding
Protein N-terminus Binding
Protein Binding
Phospholipid Binding
Neurexin Family Protein Binding
Metal Ion Binding
Biological Process
Platelet Degranulation
Developmental Process Involved In Reproduction
Intracellular Protein Transport
Vesicle Docking Involved In Exocytosis
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Axon Target Recognition
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Priming
Synaptic Vesicle Maturation
Vesicle-mediated Transport
Negative Regulation Of Protein-containing Complex Assembly
Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Negative Regulation Of Synaptic Transmission, GABAergic
Response To Estradiol
SNARE Complex Assembly
Regulation Of SNARE Complex Assembly
Positive Regulation Of Mast Cell Degranulation
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Calcium Ion-dependent Exocytosis
Protein Stabilization
Long-term Synaptic Depression
Platelet Aggregation
Cellular Response To Interferon-gamma
Protein Localization To Plasma Membrane
Presynaptic Dense Core Vesicle Exocytosis
Positive Regulation Of Vesicle Docking
Positive Regulation Of Glutamate Secretion, Neurotransmission
Regulation Of Acrosomal Vesicle Exocytosis
Plasma Membrane Repair
Platelet Degranulation
Intracellular Protein Transport
Exocytosis
Lysosome Localization
Positive Regulation Of Exocytosis
Negative Regulation Of Insulin Secretion
Positive Regulation Of Protein Secretion
Multivesicular Body Sorting Pathway
Regulation Of Plasma Membrane Repair
Pathways
Regulation of insulin secretion
Neurexins and neuroligins
Platelet degranulation
Drugs
Insulin pork
Diseases
Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS
Body size at age 10 (
32376654
)
Whole brain grey matter density (
31530798
)
Lean body mass (
28552196
)
Mean platelet volume (
32888494
)
Platelet distribution width (
32888494
)
Interacting Genes
34 interacting genes:
APBA1
APBA2
APP
BRME1
CDK5
CDK5R1
CENPP
DOC2A
DOC2B
HGS
MAPK1
MAPT
MEOX2
MTDH
MTNR1A
NEFH
NEFM
PLD1
PLD2
PRKCA
PRKCB
PRKCG
SPICE1
SPTBN1
SQSTM1
STX19
STX1A
STX1B
STX2
STX3
STX5
SYTL4
TRIM38
USO1
27 interacting genes:
CCDC85B
CEP70
DVL3
FCHO1
FXR2
HMG20A
INS
KIFC3
LMO1
LZTS1
OSBPL3
PRKAR1B
RAB27A
RAB27B
RAB3A
RAB3D
RAB8A
ROPN1
SPANXN2
STX1A
STXBP1
TBC1D1
TRIM37
TRIM41
ZBTB7B
ZBTB9
ZRANB1
Entrez ID
6812
94121
HPRD ID
04235
06735
Ensembl ID
ENSG00000136854
ENSG00000102362
Uniprot IDs
P61764
A0A024RCF8
A8K973
B2R7R4
Q71SF7
Q96C24
PDB IDs
6L03
2CSZ
3FDW
5X6T
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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